Results 121 to 130 of about 460,977 (283)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
USER-CENTERED DESIGN FOR GLOBAL INFORMATION SYSTEMS
Issues in Information Systems, 2007 Susan Conners, Roy Foreman
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Jurnal Teknologi Informasi dan Ilmu KomputerPola makan yang tidak sehat berpotensi menyebabkan gangguan gizi, seperti status gizi lebih atau status gizi kurang. Maka, penting mangatur dan memantau pola makan sehat sehingga memperoleh asupan gizi seimbang.
Irsa Ainun Nisa Sofia Nur Rohma Faiza +2 more
doaj +3 more sources
SymbolDesign: A User-centered Method to Design Pen-based Interfaces and Extend the Functionality of Pointer Input Devices [PDF]
, 2005 A method called "SymbolDesign" is proposed that can be used to design user-centered interfaces for pen-based input devices. It can also extend the functionality of pointer input devices such as the traditional computer mouse or the Camera Mouse, a ...
Betke, Margrit +2 more
core +1 more source
User-centered design of identity and access management systems
, 2014 IT security management (ITSM) technologies are important components of IT security in organizations. But there has been little research on how ITSM technologies should incorporate human and social issues into their design. Identity and Access Management (IAM) systems, as an important category of ITSM, share such a gap with other ITSM technologies.
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Innovative collaborative design in international interaction design summer schools [PDF]
, 2009 [About the book]: Design is changing, and to educate the next generation of designers, these changes need to be addressed. In light of the growing role research and interdisciplinary collaboration play in contemporary design performance, Design ...
Schadewitz, Nicole
core
Foundations for Designing User-Centered Systems [PDF]
, 2014 Frank E. Ritter +2 more
openaire +1 more source