Results 221 to 230 of about 460,977 (283)

AI-Based Gait Analysis System for Rehabilitation: Usability Evaluation of Human-Technology Interaction. [PDF]

JMIR Rehabil Assist Technol
Hong S, Choi H, Kweon H.
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Human-centered design of an artificial intelligence monitoring system: the Vanderbilt Algorithmovigilance Monitoring and Operations System. [PDF]

JAMIA Open
Salwei ME, Davis SE, Reale C, Novak LL, Walsh CG, Beebe R, Nelson S, Sundrani S, Rose S, Wright A, Ripperger M, Shave P, Embí P.   +12 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Development of an HPV 16 rapid test founded in user-centered design with primary care clinicians.

Anal Methods
Brennan LP, Hamacher F, Claure LA, Claure Dips AL, Sembian S, Balian LN, Piepho AD, Ermel AC, Linnes JC, Rodriguez NM.   +9 more
europepmc   +1 more source

Beyond models: a paradigm shift toward human-centered AI system design. [PDF]

Crit Care
Abu Hussein NS, Del Pillar Arias M, Marshall DC, Mullins C, Mwavu R, Oliver S, Sadrolashrafi M, Sim D, Komorowski M.   +8 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Opportunities and Challenges for Designing in Connected Health: Insights From an Expert Workshop.

J Med Internet Res
Premanandan S, Ahmad A, Jaranka A, Üreten E, Lee E, Gross J, Cajander Å, Ouhbi S, Lárusdóttir M, Eriksson O, Öhlund SE.   +10 more
europepmc   +1 more source

Redefining Prosthetic Needs: Insights from Individuals with Upper Limb Loss-A Systematic Review. [PDF]

Sensors (Basel)
Caldas A, Matos D, de Eyto A, Martins N.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source