Results 141 to 150 of about 5,175,775 (316)

Development of iGET Living, a Digital Graded Exposure Intervention for Youth With Chronic Pain: Multiphase User-Centered Design and Pilot Study. [PDF]

JMIR Form Res
Harrison LE, Webster SN, Choate ES, Mayanja D, Jehl N, Darnall BD, Stinson JN, Bonnert M, Lalouni M, Wicksell RK, Simons LE.   +10 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Accessible data collection methods in clinical trials: do current best practices for the implementation of electronic patient-reported outcome measures (ePROMs) meet accessibility standards? [PDF]

J Patient Rep Outcomes
Mowlem FD, O'Donohoe P.
europepmc   +1 more source

The Zero-Information-Limit Condition and Spurious Inference in Weakly Identified Models [PDF]

The fact that weak instruments lead to spurious inference is now widely recognized. In this paper we ask whether spurious inference occurs more generally in weakly identified models.
Charles Nelson, Richard Startz
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A qualitative study exploring patient and healthcare practitioner perspectives about at-home fetal Doppler devices. [PDF]

NPJ Womens Health
Keating S, Mackay R, Maclellan J, McNiven A, Dixon S.   +4 more
europepmc   +1 more source

Bootstrap Methods for Inference in a SUR model with Autocorrelated Disturbances [PDF]

Although the Parks (1967) estimator for a SUR model with AR disturbances is efficient both asymptotically and in small samples, Kmenta and Gilbert (1970) and more recently Beck and Katz (1995) note that estimated standard errors tend to be biased ...
Clarisse Messemer, Richard Parks
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Understanding Social Support and Opinion Leaders in a Tuberculosis-Related Online Community in China: Content and Network Analyses. [PDF]

JMIR Infodemiology
Fan X, Zhang J, Wang X.
europepmc   +1 more source

Transforming Bad Banks into Good Banks: Lessons from the Chilean Financial Crisis [PDF]

This paper provides a narrative account of the 1980s Chilean banking crisis. The Chilean crisis saw the nationalization of the two largest financial conglomerates and resulted in more than half of the financial system’s assets and liabilities falling ...
Philip L. Brock
core