Results 111 to 120 of about 810,480 (305)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

PrivateJobMatch: A Privacy-Oriented Deferred Multi-Match Recommender System for Stable Employment [PDF]

open access: yes, 2019
Coordination failure reduces match quality among employers and candidates in the job market, resulting in a large number of unfilled positions and/or unstable, short-term employment.
Saini, Amar
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Analisis Penerapan Sistem Report Center Dengan Metode Tam Pada Koperasi Di YOGYAKARTA [PDF]

open access: yes, 2012
Department of Industry Trade and Cooperation (Disperindagkop) DIY Province is one government office in Yogyakarta province that houses all the existing UKM and cooperation in the province of Yogyakarta.
Kusrini, K. (Kusrini)   +2 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

A model to improve user acceptance of e-services in healthcare systems based on technology acceptance model: an empirical study. [PDF]

open access: yesJ Ambient Intell Humaniz Comput, 2023
Nazari-Shirkouhi S   +3 more
europepmc   +1 more source

Development of an instrument to measure smart card technology acceptance [PDF]

open access: yes, 2009
Recently smart card is used all over the world in different applications such as financial, telecommunication, network, and physical access where the security is considered very crucial. User acceptance is very significant in successful implementation of
Ismail, Zuraini   +2 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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