Results 171 to 180 of about 146,507 (264)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Report on user acceptance

open access: yes
The Report on user acceptance in M34 will include the analysis of the surveys on the acceptability of the 5G technology and the 5GMOBIX use ...
openaire   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

User acceptance study

open access: yes
User acceptance study.9.4 and 9.5 Results of User acceptance study according to Subtask 9.5.1 and organization of OI & stakeholder workshops (Chapter 2.2.2) according to Task 9.4 in different European countries during the project: UMC (2), CHT (1) and MUW (1), BTI (2). Results of “Intimate Implant: A public engagement project” (UMC).
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Health-Enabling Technologies for Telerehabilitation of the Shoulder: A Feasibility and User Acceptance Study. [PDF]

open access: yesMethods Inf Med, 2020
Steiner B   +11 more
europepmc   +1 more source

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