Results 81 to 90 of about 810,480 (305)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
User Acceptance Of Location-Based Services
, 2008 Location-based services (LBS) exploit the known location of a user to provide services dependent on their geographic context and personalized needs [1]. The development and arrival of broadband mobile data networks supported with mobile terminals equipped with new location technologies like GPS have finally created opportunities for implementation of ...
Vrček, Neven +2 more
openaire +3 more sources
User acceptance of open enterprise solution: the OSS-ERP case [PDF]
, 2009 Organizations implement Enterprise Resource Planning (ERP) systems with the objective of reaching operational efficiency and the incorporation to new markets through the information flow control on time of the entire organization.
Bueno Ávila, Salvador +2 more
core
Non-functional Requirements Documentation in Agile Software Development: Challenges and Solution Proposal [PDF]
, 2017 Non-functional requirements (NFRs) are determinant for the success of software projects. However,they are characterized as hard to define, and in agile software development(ASD), are often given less priority and usually not documented. In this paper, we
Behutiye, Woubshet +4 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Determinants of User Acceptance of Digital Libraries
Türk Kütüphaneciliği, 2013 Using the Decomposed Theory of Planned Behavior this research aims to determine the factors that affect the intentions of teaching staff towards using digital library services.
F. Zeynep Özata, Mesut Kurulgan
doaj
WordMap: Text Mining Application of Enhanced Corpus Segmentation and Semantic Topic Recognition
Applied SciencesThis study presents WordMap, an integrated text mining application developed to enhance the efficiency and usability of text analysis over a network. As unstructured text data continues to grow across domains, effective tools for segmentation and topic ...
Zhijian Wei +4 more
doaj +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source