Results 51 to 60 of about 275,923 (298)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

User and stakeholder perspective taking in novice design teams

open access: yesDesign Science, 2022
Taking the perspective of users and stakeholders can help designers incorporate human-centricity in their practice. However, we know relatively little of the dynamics of perspective taking – a cognitive facet of empathy – in design processes as a ...
Antti Surma-aho   +2 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Meeting Multi-User Needs in Early Design Stages: A Data-Driven Conceptual Framework for Smart and Sustainable Packaging

open access: yesApplied Sciences
Effective design is becoming increasingly necessary to shorten product development times to meet evolving user demands. Thus, it is essential that designers uncover user requirements and translate them into tangible product specifications, but with the ...
Tamasine Camilleri   +3 more
doaj   +1 more source

Towards a user-centric and multidisciplinary framework for designing context-aware applications [PDF]

open access: yes, 2003
Research into context-aware computing has not sufficiently addressed human and social aspects of design. Existing design frameworks are predominantly software orientated, make little use of cross-disciplinary work, and do not provide an easily ...
Bradley, N.A., Dunlop, M.D.
core   +3 more sources

User-created persona: Namibian rural Otjiherero speakers [PDF]

open access: yes, 2015
Persona is a communicative artefact for usability that currently functions under the umbrella of User-Centred Design (UCD). Since we argue usability methods differ across cultures, this project presents a cross-cultural research probe on persona ...
Cabrero, Daniel G.
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Conceptualising Benefits of User-Centred Design for Digital Library Services

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2018
Libraries are increasingly adopting user-centred design (UCD) approaches to the development of their services for the benefit of customers. Less attention is paid to evaluating the activity of designing.
Heli Kautonen, Marko Nieminen
doaj   +1 more source

Modeling the early stages of a user-centered process in architectural design through adaptation of the methodologies of New Product Design [PDF]

open access: yes, 2009
In order to reach a degree of quality in architectural buildings that is likely to lead to user satisfaction, architectural design relies on integrating user-related information even before generation of building concepts.
BOUCHARD, Carole   +2 more
core   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy