Results 31 to 40 of about 37,804 (303)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Appropriateness of User Fees for Reproductive Health in Malawi [PDF]
The introduction of cost-sharing strategies, such as user-fees, for health care in developing countries has received increasing attention due to declining Government expenditure on health and reduced donor funding.
Hennink, Monique, Madise, Nyovani
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
"November 18, 1998."; Discusses 22a-482-3(e) of the Connecticut agency regulations regarding user ...
Goranson, Susan,
core
Reducing user fees for primary health care in Kenya: Policy on paper or policy in practice?
Background Removing user fees in primary health care services is one of the most critical policy issues being considered in Africa. User fees were introduced in many African countries during the 1980s and their impacts are well documented.
Goodman Catherine +4 more
doaj +1 more source
How Did Local Governments Recover Their Financial Condition? Lessons from Citizen Participation
This study offers lessons for overcoming future economic crises by examining whether democratic management helped local governments recover their financial condition.
Ji Hyung Park
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
International aeronautical user charges [PDF]
February 1985Includes bibliographical referencesIntroduction: 1.1 BACKGROUND AND MOTIVATION Very few issues relating to the international air transportation industry are today as divisive as those pertaining to user charges imposed at international ...
Odoni, Amedeo R.
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

