Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
Utilização de benzodiazepínicos e estratégias farmacêuticas em saúde mental
O artigo enfoca a heterogeneidade no uso de benzodiazepínicos, sob o enfoque farmacêutico, observada nos Centros de Atenção Psicossocial e Unidades Básicas de Saúde da Família.
Gabriela de Almeida Ricarte Correia +1 more
doaj +1 more source
Java in the High Performance Computing arena: Research, practice and experience [PDF]
This is a post-peer-review, pre-copyedit version of an article published in Science of Computer Programming. The final authenticated version is available online at: https://doi.org/10.1016/j.scico.2011.06.002[Abstract] The rising interest in Java for ...
Doallo, Ramón +4 more
core +2 more sources
Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source
Acolhimento e Resolubilidade das Urgências na Estratégia Saúde da Família
O objetivo deste estudo de abordagem qualitativa foi analisar o acolhimento e a resolubilidade das situações de urgência no âmbito da Estratégia Saúde da Família (ESF). Foram realizadas 27 entrevistas com profissionais de equipes de Saúde da Família, que,
Deborah Curvelo de Farias +4 more
doaj +1 more source
Objectives: To assess the interaction between mental health and primary care, as well as analyze if these services enable the embracement process and reintegration of users in family and community. Methods: An exploratory study with qualitative approach
Francisca Bezerra de Oliveira +3 more
doaj +1 more source
Contribution of a shelter-based Integrated Management of Childhood Illnesses Program for children under the age of five years [PDF]
OBJETIVO: Descrever o acolhimento, estruturado pela Atenção Integrada às Doenças Prevalentes na Infância, às crianças menores de cinco anos, em unidade de saúde da família. MÉTODOS: Estudo descritivo.
LUNARDELO, Simone Renata +3 more
core +2 more sources
Why Didn't I Get a Payout? Understanding Farmer Choices, Index Insurance, and Basis Risk
ABSTRACT Index insurance, while heralded as a potential solution to alleviate poverty and food insecurity among agricultural households, has its own set of challenges, notably basis risk. Basis risk is the discrepancy between the insurance payout and losses incurred, posing a significant deterrent to the adoption of index insurance.
S. Lucille Blakeley +4 more
wiley +1 more source
User embracement in the Family Health Strategy in a city in the north of Minas Gerais, Brazil: a descriptive study, 2019-2020. [PDF]
Barbosa SFA +3 more
europepmc +1 more source
ICOPER Project - Deliverable 4.3 ISURE: Recommendations for extending effective reuse, embodied in the ICOPER CD&R [PDF]
The purpose of this document is to capture the ideas and recommendations, within and beyond the ICOPER community, concerning the reuse of learning content, including appropriate methodologies as well as established strategies for remixing and repurposing
Connolly, Teresa +3 more
core

