Results 91 to 100 of about 4,336 (317)

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Utilização de benzodiazepínicos e estratégias farmacêuticas em saúde mental

open access: yesSaúde em Debate
O artigo enfoca a heterogeneidade no uso de benzodiazepínicos, sob o enfoque farmacêutico, observada nos Centros de Atenção Psicossocial e Unidades Básicas de Saúde da Família.
Gabriela de Almeida Ricarte Correia   +1 more
doaj   +1 more source

Java in the High Performance Computing arena: Research, practice and experience [PDF]

open access: yes, 2013
This is a post-peer-review, pre-copyedit version of an article published in Science of Computer Programming. The final authenticated version is available online at: https://doi.org/10.1016/j.scico.2011.06.002[Abstract] The rising interest in Java for ...
Doallo, Ramón   +4 more
core   +2 more sources

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

Acolhimento e Resolubilidade das Urgências na Estratégia Saúde da Família

open access: yesRevista Brasileira de Educação Médica
O objetivo deste estudo de abordagem qualitativa foi analisar o acolhimento e a resolubilidade das situações de urgência no âmbito da Estratégia Saúde da Família (ESF). Foram realizadas 27 entrevistas com profissionais de equipes de Saúde da Família, que,
Deborah Curvelo de Farias   +4 more
doaj   +1 more source

(Re) Constructing scenarios for action in mental health in the Family Health Strategy - doi:10.5020/18061230.2011.p109

open access: yesRevista Brasileira em Promoção da Saúde, 2012
Objectives: To assess the interaction between mental health and primary care, as well as analyze if these services enable the embracement process and reintegration of users in family and community. Methods: An exploratory study with qualitative approach
Francisca Bezerra de Oliveira   +3 more
doaj   +1 more source

Contribution of a shelter-based Integrated Management of Childhood Illnesses Program for children under the age of five years [PDF]

open access: yes, 2009
OBJETIVO: Descrever o acolhimento, estruturado pela Atenção Integrada às Doenças Prevalentes na Infância, às crianças menores de cinco anos, em unidade de saúde da família. MÉTODOS: Estudo descritivo.
LUNARDELO, Simone Renata   +3 more
core   +2 more sources

Why Didn't I Get a Payout? Understanding Farmer Choices, Index Insurance, and Basis Risk

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Index insurance, while heralded as a potential solution to alleviate poverty and food insecurity among agricultural households, has its own set of challenges, notably basis risk. Basis risk is the discrepancy between the insurance payout and losses incurred, posing a significant deterrent to the adoption of index insurance.
S. Lucille Blakeley   +4 more
wiley   +1 more source

ICOPER Project - Deliverable 4.3 ISURE: Recommendations for extending effective reuse, embodied in the ICOPER CD&R [PDF]

open access: yes, 2011
The purpose of this document is to capture the ideas and recommendations, within and beyond the ICOPER community, concerning the reuse of learning content, including appropriate methodologies as well as established strategies for remixing and repurposing
Connolly, Teresa   +3 more
core  

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