Results 41 to 50 of about 238,671 (263)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Approach Integration Design Sprints to Design Thinking in Learning Management System Sakattaku

open access: yesKhazanah Informatika
The Ministry of Education and Culture has introduced a new phase of its independent learning policy called the Movement Organization Program (POP). As a participant in POP, the Sakata Innovation Center Foundation offers a Saung Coding training program ...
Siti Nabilah Nida   +2 more
doaj   +1 more source

ANALISIS DAN PERANCANGAN INTERAKSI CHATBOT REMINDER DENGAN USER-CENTERED DESIGN

open access: yesJurnal Sistem Informasi, 2017
Keberadaan teknologi yang tidak dipersiapkan untuk menghadapi interaksi dengan pengguna akan membuat user experience menjadi buruk. Masih banyak ditemukan chatbot reminder yang tidak dapat memenuhi harapan pengguna.
Ahmad Alim Akhsan, Faizah Faizah
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Free for All

open access: yesJournal of New Librarianship
Periodic website redesign projects have become essential -- though often complex and costly -- measures that libraries take to ensure users’ ease of access to resources.
Victoria Elmwood   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Measuring the Spatial-Temporal Heterogeneity of Helplessness Sentiment and Its Built Environment Determinants during the COVID-19 Quarantines: A Case Study in Shanghai

open access: yesISPRS International Journal of Geo-Information
The COVID-19 outbreak followed by the strict citywide lockdown in Shanghai has sparked negative emotion surges on social media platforms in 2022. This research aims to investigate the spatial–temporal heterogeneity of a unique emotion (helplessness) and ...
Yuhao He   +4 more
doaj   +1 more source

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