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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Content Reuse and Interest Sharing in Tagging Communities [PDF]
Tagging communities represent a subclass of a broader class of user-generated content-sharing online communities. In such communities users introduce and tag content for later use.
Iamnitchi, Adriana +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cruise Passengers' Perceived Service Quality During the Pandemic Period via User-Generated Content
The coronavirus epidemic, which emerged in Wuhan at the end of 2019, spread worldwide and caused more than 4 million deaths as of 2021. The cruise industry, whose goal is to maintain customer satisfaction at the highest possible level, like all service ...
Batuhan Çullu +2 more
doaj +1 more source
Comparing Data-Driven Methods for Extracting Knowledge from User Generated Content
This study aimed to compare two techniques of business knowledge extraction for the identification of insights related to the improvement of digital marketing strategies on a sample of 15,731 tweets.
Jose Ramon Saura +2 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Integrated content presentation for multilingual and multimedia information access [PDF]
For multilingual and multimedia information retrieval from multiple potentially distributed collections generating the output in the form of standard ranked lists may often mean that a user has to explore the contents of many lists before finding ...
Jones, Gareth J.F., Wade, Vincent
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
On Reverse Dracula and Picky Bites – introduction to study of Urban Dictionary
This article provides an introductory examination of Urban Dictionary, focusing on its attributes and distinctive features. In the article the functionalities of the webpage are explored, the structure of entries is analysed and a typology of ...
Izabela Walczak
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

