Results 91 to 100 of about 5,316,996 (342)
Involving Consumers: The Role of Digital Technologies in Promoting ‘Prosumption’ and User Innovation
Journal of the Knowledge Economy, 2016 Since the First Industrial Revolution, consumers have been mainly considered as playing a passive role with regard to production. However, the recent decades have seen a progressive growth in consumer involvement in production processes, for instance, in
Thierry Rayna, L. Striukova
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
PLoS ONE, 2016 Background In order to adapt to societal changes, healthcare systems need to switch from a disease orientation to a patient-centered approach. Virtual patient networks are a promising tool to favor this switch and much can be learned from the open and ...
J. Amann, Claudia Zanini, S. Rubinelli
semanticscholar +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Innovation is created by humans, not by systems: an exploration of user involvement in living labs: user motivation versus lead user criteria [PDF]
, 2014 The past few years companies have become more interested in involving users during the production process of their products. On the other hand, a group of users started to innovate on their own.
Logghe, Sara +2 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Multiple Information Devices Users in the Era of Digital Convergence
Annals of Business Administrative Science, 2017 Predictions of a coming age of digital convergence bring to mind a convergence of the information devices used by consumers. In actuality, information devices are becoming more diversified.
Takeyasu ICHIKOHJI, Sotaro KATSUMATA
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Open, distributed and user-centered: Towards a paradigm shift in innovation policy [PDF]
Today's innovation policies ignore that innovation is increasingly open, distributed and user-centered. In this paper we introduce the user-centered model as an alternative paradigm of how innovation 'works'.
Eric von Hippel, Jeroen de Jong
core
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Dynamic Relationships Management Journal (DRMJ), 2019 This paper carries out a systematic and up‐to‐date literature review in the domain of user innovation (UI). Unlike previous reviews, this paper scrutinizes the “locus” of UI, meaning it distinguishes between studies focusing on external‐to‐the‐firm ...
Khatereh Ghasemzadeh
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