Results 31 to 40 of about 129,266 (215)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Comparative Analysis and Prospect of Standard System for New Energy Storage Systems
发电技术ObjectivesIn order to provide directional reference and strategic basis for promoting the standardization and normative development of new energy storage systems in China, it is necessary to evaluate the completeness and applicability of existing energy ...
LI Jianlin +5 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
IET Generation, Transmission & DistributionThis paper proposes a distributed cooperative control scheme for multiple energy storage unit (ESU) in DC microgrids to achieve the control objectives of SoC balancing, power sharing, and bus voltage recovery.
Jianlin Li, Honghao You
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Tools for Tooling: Digital Fabrication Technology as the Innovation Enabler
Arts, 2019 This paper describes research concerning the creation of a novel sheet glass forming system based on the Reconfigurable Pin Tooling (RPT) principle. The paper will initially outline some of the theoretical and technical background for the research. These
Tavs Jorgensen
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
User Innovation: State of the Art and Perspectives for Future Research
Journal of Entrepreneurship, Management and Innovation, 2017 Given the rising role of users in innovaton processes and the increasing amount of research in this feld the aim of this paper is to explore the limits of our understanding of the user innovaton (UI) concept.
Maria Roszkowska-Menkes
doaj +1 more source
Co-Innovation between a Lead User and Producers:
Maketingu Janaru, 2019 In this paper, we discuss co-innovation between Lead Users and Producers. To practically apply the user innovation theory to product development, two methods have been used: the lead user method and user-community based theory.
Manabu Mizuno, Takahiko Kozuka
doaj +1 more source