Results 61 to 70 of about 129,266 (215)
The Impact of Differences in Regulatory Focus on the Originator Effect of User-Generated Products
Maketingu JanaruWith the evolution of digital technology, the development of new products that are co-created by users is increasing. Research has revealed the existence of the “originator effect”, which increases consumers’ purchase intentions by informing them that a ...
Shoo Okada
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Multiple Information Devices Users in the Era of Digital Convergence
Annals of Business Administrative Science, 2017 Predictions of a coming age of digital convergence bring to mind a convergence of the information devices used by consumers. In actuality, information devices are becoming more diversified.
Takeyasu ICHIKOHJI, Sotaro KATSUMATA
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Dynamic Relationships Management Journal (DRMJ), 2019 This paper carries out a systematic and up‐to‐date literature review in the domain of user innovation (UI). Unlike previous reviews, this paper scrutinizes the “locus” of UI, meaning it distinguishes between studies focusing on external‐to‐the‐firm ...
Khatereh Ghasemzadeh
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Open Innovation Processes in Living Lab Innovation Systems: Insights from the LeYLab [PDF]
Technology Innovation Management Review, 2013 Living labs have emerged on the crossroads of the open innovation and user innovation frameworks. As open innovation systems, living labs consist of various actors with each playing their specific role.
Dimitri Schuurman +2 more
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IEEE Access, 2019 The construction of user innovation knowledge map can clearly describe the co-occurrence relationship among innovative knowledge points. Different types of weighted knowledge map models have been applied by enterprises to promote their innovative ...
Qiaojiayu Wang +3 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source