Results 111 to 120 of about 202,245 (312)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The Design and evaluation of the specification framework for user interface design

This thesis presentsthe design and evaluation of an interface specification meta-language(ISML) that has been developed to explicitly support metaphor abstractions in a model-based, user interface design framework.
Crowle, Simon
core  

Applicability of HCI Techniques to Systems Interface Design

, 1990
PhDThis thesis seeks to identify reasons why HCI techniques are unsuitable for application in real world design projects. User-oriented systems design and evaluation require that many considerations such as the psychology of users, the applications and
Bellotti, Victoria Mary Elizabeth
core  

User-defined interface gestures : dataset and analysis

, 2014
We present a video-based gesture dataset and a methodology for annotating video-based gesture datasets. Our dataset consists of user-defined gestures generated by 18 participants from a previous investigation of gesture memorability.
Per Ola Kristensson, Kristensson, Per Ola, Miguel A. Nacenta, Nacenta, Miguel, Grijincu, Daniela, Miguel Nacenta, Daniela Grijincu   +6 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

User Experience Research pada Google Maps dengan Penambahan Fitur Driving Behavior Menggunakan Metode User Centered Design

Jurnal Informatika dan Multimedia
Kecelakaan lalu lintas merupakan penyebab kematian nomor dua di dunia. Indonesia menduduki peringkat kedua penyebab kematian tertinggi akibat kecelakaan lalu lintas. Statistik kecelakaan lalu lintas menunjukkan bahwa sebagian besar kecelakaan disebabkan
Novitasari
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Avaliação da interface de um aplicativo computacional através de teste de usabilidade, questionário ergonômico e análise gráfica do design [PDF]

, 2003
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.O presente trabalho apresenta os conceitos envolvidos com a interface, aspectos ligados ao perfil do usuário e ...
Barros, Vanessa Tavares de Oliveira
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source