Results 111 to 120 of about 662,603 (329)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Uma abordagem baseada em XML para construção de Interfaces de Usuário para Múltiplos Dispositivos = A XML-based approach for building multi-device user interfaces

Acta Scientiarum: Technology, 2006
O desenvolvimento de aplicações para múltiplos dispositivos leva emconsideração diferentes características e restrições de cada dispositivo. Linguagens de especificação de interfaces e modelos arquiteturais têm sido utilizados por projetistas de ...
Ayslan Trevizan Possebom, Antonio Mendes da Silva Filho, Sérgio Roberto Pereira da Silva   +2 more
doaj  

Interactions of the Future: The Relationship Between Screenless Interfaces and User Experience Design

Art Time
Traditional screen-based interfaces are evolving into a new era due to rapid technological advancements and shifting user needs. At the core of this evolution lies Anderson's 1989 vision of computer technology becoming transparent and invisible to the ...
Sevim Burçak Maraşlı, Ziyacan Bayar
doaj   +1 more source

Multi-silicone bilateral soft physical twin as an alternative to traditional user interfaces for remote palpation: a comparative study. [PDF]

Sci Rep, 2023
Costi L, Iida F.
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

User interfaces for actuated scope maneuvering in surgical systems: a scoping review. [PDF]

Surg Endosc, 2023
Hamza H, Baez VM, Al-Ansari A, Becker AT, Navkar NV.   +4 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Designing user interfaces for content simplification aimed at people with cognitive impairments. [PDF]

Univers Access Inf Soc, 2023
Moreno L, Petrie H, Martínez P, Alarcon R.   +3 more
europepmc   +1 more source