Ocean services user needs assessment. Volume 1: Survey results, conclusions and recommendations [PDF]
An interpretation of environmental information needs of marine users, derived from a direct contact survey of eight important sectors of the marine user community is presented. Findings of the survey and results and recommendations are reported.
Mccandless, S. W. +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
User needs gathering for the design of information and communications technology-supported occupational stress management intervention: A quantitative study. [PDF]
Digit Health, 2022 Weerasekara M +3 more
europepmc +1 more source
Spacecraft Systems Working Group report [PDF]
Issues addressed include: definition of user/commercial/government needs by function; criteria for prioritization of needs; overall criteria for technology assessment; system configuration drivers (key trade studies); space infrastructure interface; and ...
Keigler, John E., Rowell, Larry F.
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Chronic pain self-management in middle-aged and older adults: A collective intelligence approach to identifying barriers and user needs in eHealth interventions. [PDF]
Digit Health, 2022 O'Reilly PM +5 more
europepmc +1 more source
Using design principles as a lens to interpret user needs: a case study using a new 3D tic-tac-toe game [PDF]
J. Joshua Thomas +4 more
openalex +1 more source