Results 241 to 250 of about 2,245,729 (347)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Brief description: The deliverable identifies the potential drivers of future demand for road-space on major urban roads, associated with changes in socio-demographics, lifestyles and business models. It will do this through an international literature review (academic and grey literatures in different languages) and interviews with key stakeholder ...
openaire +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
The results of surveys and interviews with PARSEC-relevant SMEs will be processed, analysed and presented, with lessons drawn to inform implementation of the project.
openaire +1 more source
Effectively publishing and disseminating Framework for Excellence (FfE): analysis of user needs : final report [PDF]
Dickinson, Peter, Farrell, Julie
core
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Taking steps towards deinstitutionalizing mental health care within a low and middle-income country: A cross-sectional study of service user needs in the Republic of Moldova. [PDF]
Frasch JJ +5 more
europepmc +1 more source

