Results 111 to 120 of about 5,239,056 (367)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Interpretation of Insecticide Posters by Rice Farmers In Selected Villages in Leyte, Philippines

Annals of Tropical Research, 2016
Farmers usually get pesticide information from different sources, such as radio, television, print ads, extension technicians, pesticide sales agents, other farmers, and their own experience.
Dennis C. Cortes, Monina Escalada
doaj   +1 more source

Prediction feedback in intelligent traffic systems

, 2009
The optimal information feedback has a significant effect on many socioeconomic systems like stock market and traffic systems aiming to make full use of resources. In this paper, we studied dynamics of traffic flow with real-time information provided and
Arnott, Ben-Akiva, Biham, Bing-Hong Wang, Chowdhury, Chuan-Fei Dong, Friesz, Guan-Wen Wang, Helbing, Helbing, Helbing, Helbing, Kachroo, Lee, Lehmann, Mahmassani, Nagatani, Nagel, Paveri-Fontana, Prigogine, Rothery, Wagner, Wahle, Wang, Xiao-Yan Sun, Xu Ma, Yokoya   +26 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Literature Review on Needs of Upper Limb Prosthesis Users

Frontiers in Neuroscience, 2016
The loss of one hand can significantly affect the level of autonomy and the capability of performing daily living, working and social activities. The current prosthetic solutions contribute in a poor way to overcome these problems due to limitations in ...
F. Cordella, A. Ciancio, R. Sacchetti, A. Davalli, A. Cutti, E. Guglielmelli, L. Zollo   +6 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

End-user Driven Feedback Prioritization

, 2017
End-user feedback is becoming more important for the evolution of software systems. There exist various communication channels for end-users (app stores, social networks) which allow them to expres ...
Seyff, Norbert, Stade, Melanie, Fotrousi, Farnaz, Glinz, Martin, Guzman, Emitza, Kolpondinos-Huber, Martina, Munante Arzapalo, Denisse, Oriol, Marc, Schaniel, Ronnie   +8 more
openaire   +4 more sources

Effects of Congruent Multisensory Feedback on the Perception and Performance of Virtual Reality Hand-Retargeted Interaction

IEEE Access
Retargeting methods that modify the visual representation of real movements have been widely used to expand the interaction space and create engaging virtual reality experiences.
Hyunyoung Jang, Jinwook Kim, Jeongmi Lee
doaj   +1 more source