Results 21 to 30 of about 400,967 (218)

When innovation outpaces regulations: The legal challenges for direct‐to‐patient supply of investigational medicinal products

British Journal of Clinical Pharmacology, Volume 88, Issue 3, Page 1115-1142, March 2022., 2022
Aims We profile the lack of specific regulation for direct‐to‐patient postal supply (DTP) of clinical trial medications (investigational medicinal products, IMPs) calling for increased efficiency of patient‐centred multi‐country remote clinical trials.
Maeve Malone, Pamela Ferguson, Amy Rogers, Isla S. Mackenzie, David A. Rorie, Thomas M. MacDonald   +5 more
wiley   +1 more source

A novel therapeutic diet can significantly reduce the medication score and pruritus of dogs with atopic dermatitis during a nine‐month controlled study

Veterinary Dermatology, Volume 33, Issue 1, Page 55-e18, February 2022., 2022
Background – Canine atopic dermatitis (cAD) is a common chronic relapsing pruritic skin disease for which management commonly relies on life‐long use of immunomodulatory drugs. A number of the medications used are associated with adverse effects and the potential for complications during long‐term use.
Adrian Watson, Ana Rostaher, Nina M Fischer, Claude Favrot   +3 more
wiley   +1 more source

Off-label pediatric medicines in Spain

Anales de Pediatría (English Edition), 2021
Since 2009, the use of off-label and unlicensed drugs has been regulated in Spain. In pediatrics, this exceptional use is more common than in other medical specialties. It varies from 10% to 90% of all prescriptions in children.
Roi Piñeiro Pérez, Esmeralda Núñez Cuadros, Belén Rodríguez Marrodán, Raquel Escrig Fernández, María Ángeles Gil Lemus, Santiago Manzano Blanco, Cristina Calvo   +6 more
doaj   +1 more source

CEFALEIA POR USO EXCESSIVO DE MEDICAMENTOS

Infarma - Ciências Farmacêuticas, 2015
Uma variante da cefaleia crônica diária, a cefaleia por uso excessivo de medicamentos é uma manifestação clínica de frequência ≥ 15 dias por mês, durante 3 meses. Possui um diagnóstico deficiente e um tratamento dividido em etapas, sendo a desintoxicação, a etapa de fundamental importância.
Ariane Maria Fonseca Miranda, Mila Pacheco, Ana Patrícia Queiroz, José Adriano Silva, Patrícia Araújo, Rosa Martins   +5 more
openaire   +2 more sources

Evaluación de las prescripciones autorizadas entre 2010 y 2011 por vía judicial en Bogotá, D.C., Colombia

Revista de la Facultad de Medicina, 2016
Introducción. La tutela es una herramienta legal empleada para garantizar el derecho a la salud en Colombia. Objetivo. Evaluar la racionalidad terapéutica de prescripciones de medicamentos autorizadas por tutela en pacientes afiliados al Sistema ...
Alfredo Portilla-Pinzón, José Julián López, Mauricio Montoya-Cañón, Jorge Enrique Machado-Alba   +3 more
doaj   +1 more source

Polifarmacia: interacciones y reacciones adversas en el uso de medicamentos por ancianos [PDF]

, 2010
O artigo tem por objetivo refletir sobre a polifarmácia em idosos com ênfase nas reações adversas e nas interações medicamentosas. A vulnerabilidade dos idosos aos problemas decorrentes do uso de medicamentos é bastante alta, o que se deve a complexidade
SECOLI, Silvia Regina
core   +2 more sources

Uso racional de medicamentos: conhecimento do utente acerca do medicamento em uso

Egitania Sciencia, 2014
Esta investigação tem como objetivos avaliar o conhecimento dos utentes acerca do medicamento em uso e verificar se existem diferenças, tendo em conta o género, as classes etárias e o nível de escolaridade. Este estudo, analítico, transversal e observacional, foi feito tendo como base uma amostra constituída por 398 indivíduos do concelho de Bragança ...
Ribeiro, Maria Isabel, Costa, Daniela, Clemente, Juliana, Fernandes, Mara, Ribeiro, Patrícia   +4 more
openaire   +2 more sources

Challenges facing drug utilization research in the Latin American region

Pharmacoepidemiology and Drug Safety, Volume 29, Issue 11, Page 1353-1363, November 2020., 2020
Abstract Purpose The International Society of Pharmacoepidemiology (ISPE) in collaboration with the Latin America Drug Utilization Research Group (LatAm DURG), the Medicines Utilization Research in Africa (MURIA) group, and the Uppsala Monitoring Center, is leading an initiative to understand challenges to drug utilization research (DUR) in the Latin ...
Maribel Salas, Luciane C. Lopes, Brian Godman, Ilse Truter, Abraham G. Hartzema, Bjorn Wettermark, Joseph Fadare, Johanita R. Burger, Kwame Appenteng, Macarius Donneyong, Ariel Arias, Daniel Ankrah, Olayinka O. Ogunleye, Martha Lubbe, Laura Horne, Jorgelina Bernet, Diana L. Gómez‐Galicia, Miriam del Carmen Garcia Estrada, Margaret N. Oluka, Amos Massele, Luis Alesso, Raquel Herrera Comoglio, Elisangela da Costa Lima, Carmen Vilaseca, Ulf Bergman   +24 more
wiley   +1 more source

Perfil de medicamentos envueltos en errores de administración: conocer para prevenir [PDF]

, 2010
OBJECTIVES: To describe the pharmacological characteristics of medicines involved in administration errors and determine the frequency of errors with potentially dangerous medicines and low therapeutic index, in clinical units of five teaching hospitals,
CASSIANI, Silvia Helena De Bortoli, GIMENES, Fernanda Raphael Escobar, LIMA, Rhanna Emanuela Fontenele, MARQUES, Tatiane Cristina, OPITZ, Simone Perufo, REIS, Adriano Max Moreira, SILVA, Ana Elisa Bauer de Camargo, TEIXEIRA, Thalyta Cardoso Alux   +7 more
core   +2 more sources

Decrease in primary but not in secondary abdominal surgery for Crohn's disease: nationwide cohort study, 1990–2014

BJS (British Journal of Surgery), Volume 107, Issue 11, Page 1529-1538, October 2020., 2020
In a Swedish population‐based database, the cumulative incidence of a first abdominal surgical procedure after a diagnosis of Crohn's disease has decreased by two‐thirds over the past 25 years. The risk of repeat abdominal surgery has not decreased since the introduction of biologicals. Ileocaecal resection remained the most common procedure during the
T. D. Kalman, Å. H. Everhov, C. Nordenvall, M. C. Sachs, J. Halfvarson, A. Ekbom, J. F. Ludvigsson, P. Myrelid, O. Olén   +8 more
wiley   +1 more source