Results 31 to 40 of about 435,133 (299)

USP-18 overexpression in RAW264.7 cells decreases production of IL-27 and IL-10.

, 2016
RAW264.7 cells were transfected with empty vector or USP-18-V5 (2 μg) for 48 hours. The cells were then incubated in the presence of LPS (200 ng/ml) or vehicle for 24 hours.
Zeyu Xiong (336705), Rama Mallampalli (3150153), Jing Zhao (21160), Bryan J. McVerry (425748), John Hollingsworth (3150144), Anastasiya Birukova (3150147), William T. Horne (120096), Miguel Pinilla-Vera (3150138), Anuradha Ray (233621), Jay K. Kolls (23226), Suchitra Barge (402117), Prabir Ray (233626), Michael P. Donahoe (3150150), Robert M. Tighe (3150141), W. Michael Foster (306647), Janet S. Lee (260230), Yutong Zhao (356724)   +16 more
core   +1 more source

Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In this study, chemoproteomics combined with genetic and functional analyses was integrated to identify SHMT2 as a covalent and functional target of gambogic acid (GA) in triple‐negative breast cancer (TNBC). Further validation demonstrated that GA selectively modifies the Cys241 site of SHMT2, triggering mitochondrial dysfunction, activating the Nrf2 ...
Tong Yang, Chong Qiu, Yulei Li, Ying Zhang, Chen Wang, Jie Zhou, Zheng Chu, Ang Ma, Ling Huang, Yin Kwan Wong, Junzhe Zhang, Peng Gao, Cui Liu, Junhua Zhang, Huan Tang, Jigang Wang   +15 more
wiley   +1 more source

Evaluación de la calidad fisicoquÍmica en cápsulas de cefalexina 500 mg

Tecnología en Marcha
El presente artículo contiene los detalles sobre el estudio realizado a la calidad fisicoquímica en las cápsulas de cefalexina de 500 mg que se comercializan en Costa Rica.
Samantha Pereira-Leiva, Esteban Pérez-López   +1 more
doaj   +1 more source

Negativas Sentenciais Pós-Verbais no Paraná

Signum: Estudos da Linguagem, 2019
O trabalho descreve as negativas sentenciais pós-verbais no português do estado do Paraná, a partir de dados do Projeto Atlas Linguístico do Brasil (ALiB), como parte de um esforço mais amplo para o mapeamento da negação sentencial em dialetos da região ...
Rerisson Cavalcante de Araújo
doaj   +1 more source

Institute of Brazilian Studies – USP

, 2009
O Instituto de Estudos Brasileiros da USP(IEB/ USP) foi fundado na década de 1960por um grupo de professores e intelectuais li-gados a esta universidade, sob a liderança deSérgio Buarque de Holanda.
Editorial, Comissão
core   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

A Review and Comparative Study of Preservative Efficacy Test in the United States, European, Indian, and Japanese Pharmacopeias and Implications for Asian Pharmacopeias

Journal of Medical Microbiology and Infectious Diseases
Introduction: The preservative efficacy test (PET) is a critical tool for assessing the ability of antimicrobial preservatives to prevent microbial contamination in pharmaceutical products, ensuring their safety and stability during production and ...
Sara Sajjadi, Fatemeh Shafizadeh, Somayeh Hallaj-Nezhadi   +2 more
doaj   +1 more source

Análise das produções científicas publicadas nos congressos de contabilidade UFSC e USP de 2008 e 2009 [PDF]

, 2010
TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisEste trabalho tem por objetivo mapear as publicações dos Congressos UFSC de Controladoria e Finanças e Iniciação Científica em Contabilidade (2008
Silva, Roberta Rodrigues da
core  

USP Serviços: um catálogo para a educação

, 1996
A publicação do catálogo USP Serviços - Educação indica novas possibilidades de integração entre a Universidade de São Paulo e o sistema educacional.The publication of the catalogue USP Serviços - Educação (USP Services - Education) indicates new ...
Soares, Vera
core   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source