Results 161 to 170 of about 1,077,298 (290)

Growth Hormone Promotes Lipolysis and Impairs Insulin Sensitivity by Activating the ERK/HSL Signaling Pathway in Bovine Adipocytes

open access: yesAnimal Research and One Health, EarlyView.
This study was to evaluate the role of GH in lipolysis and insulin sensitivity in bovine adipocytes and clarify the underlying mechanism. Our findings demonstrate that GH activates ERK/HSL signaling pathway, promotes lipolysis, and impairs insulin sensitivity in bovine adipocytes.
Xinxing Gao   +10 more
wiley   +1 more source

Copathologies of Limbic-Predominant Age-Related TDP-43 Encephalopathy and Alzheimer Disease: [<sup>18</sup>F]FDG PET Statistical Mapping and Quantitative MRI Volumetry. [PDF]

open access: yesJ Nucl Med
Ngam PI   +7 more
europepmc   +1 more source

Performance of the Predicting Risk of Cardiovascular Disease Events Calculator in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Evaluate performance of the Predicting Risk of Cardiovascular Disease Events (PREVENT) calculator in rheumatoid arthritis (RA). Methods Patients with RA were matched up to 10 controls on age, sex, and enrollment year using National Veterans Health Administration, Medicare, and National Death Index data (2006–2020).
Tate M. Johnson   +13 more
wiley   +1 more source

Pregnancy outcomes in women with Von Willebrand disease: a statewide cohort study. [PDF]

open access: yesRes Pract Thromb Haemost
Lim MY   +3 more
europepmc   +1 more source

Inferring rheumatoid arthritis disease activity status from the electronic health records across health systems

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHR) data has limited the ability to generate real‐world evidence (RWE). This study aimed to develop and validate scalable machine learning (ML) models to infer
David Cheng   +34 more
wiley   +1 more source

Independent and interactive effects of wet bulb globe temperature and air pollution exposures on suicide mortality. [PDF]

open access: yesEnviron Int
Lamichhane DK   +11 more
europepmc   +1 more source

The paper puzzle as an active learning tool in the teaching of anatomy: A qualitative study of perceptions in students and near‐peer teachers

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Active learning strategies enhance medical education by fostering self‐directed learning, communication, and problem‐solving skills. The paper puzzle, a game‐based learning approach, provides an engaging way to reinforce anatomical knowledge and promote collaboration.
Ricardo Tello‐Mendoza   +6 more
wiley   +1 more source

GARDE-Chat: a scalable, open-source platform for building and deploying health chatbots. [PDF]

open access: yesJ Am Med Inform Assoc
Del Fiol G   +22 more
europepmc   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

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