Results 151 to 160 of about 578,573 (268)

CCNE1: A Cell Cycle Regulator That Influences Tumor Progression

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACTCyclin E1 (CCNE1), a pivotal member of the cyclin family, governs the G1/S phase transition of the cell cycle by binding to and activating cyclin‐dependent kinase 2 (CDK2), thereby initiating DNA replication and driving S‐phase entry. In a broad spectrum of human malignancies—including breast, ovarian, gastric, and non‐small cell lung cancers ...
Liang Yan, Siyi Liu, Yanling Li, Qian He, Chen Long, Ning Tang, Yanhong Zhou   +6 more
wiley   +1 more source

Next‐Generation Sequencing‐Based Molecular Profiling and Management of Advanced Solid Tumors: A Real‐World Experience in a Community‐Based Academic Cancer Center

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Advances in molecular and cell biology have led to a paradigm shift in cancer management. We implemented next‐generation sequencing (NGS) at our community‐based academic cancer center over a decade ago. We sought to optimize the use of genomics and understand its impact in identifying actionable genomic alterations to determine ...
Gayathri Moorthy, Annette Sereika, Karen Kaul, Megan Parilla, Mir B. Alikhan, Michael Bouma, Dyson Wake, Peter J. Hulick, Henry M. Dunnenberger, Linda M. Sabatini, Mathew Yang, Kathy A. Mangold, Erin Proctor, Nicholas Evans, Nicholas Miller, Donald L. Helseth Jr, Darryck Maurer, Justin Brueck, Janardan Khandekar, Bruce Brockstein   +19 more
wiley   +1 more source

Cervical metastasis of breast cancer: a case report and review of the literature

Discover Oncology
Metastatic breast cancer (BC) to the cervix is relatively rare among women with BC. Although the most common histopathological type of BC is invasive ductal carcinoma, invasive lobular carcinoma is more likely to metastasize to the female reproductive ...
Yuping Shan, Feng Hou, Yan Wang, Yi Han, Zhumei Cui, Guangjie Yin   +5 more
doaj   +1 more source

Pre‐Existing and Post‐Cancer Major Cardiovascular Disease and Their Association With Mortality Outcomes Among Cancer Survivors in Australia

Cancer Medicine, Volume 15, Issue 10, October 2026.
Pre‐existing and post‐cancer major cardiovascular disease and their association with mortality among cancer survivors in Australia. ABSTRACT Background As cancer survival improves, cardiovascular disease (CVD) has emerged as a major competing cause of death.
Md Mijanur Rahman, Katy Bell, Grace Joshy, Michael David, Karen Canfell, David Goldsbury, Bogda Koczwara, Emily Banks, Kazuaki Negishi, Geoff P. Delaney, Mei Ling Yap, Xue Qin Yu   +11 more
wiley   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

Desempenho do exame citológico e da captura híbrida II no rastreamento de lesões intraepiteliais escamosas de alto grau em mulheres HIV+

Cadernos de Saúde Pública
As lesões intraepiteliais escamosas de alto grau (HSIL) são precursoras do câncer do colo do útero, com maior risco de ocorrência e desenvolvimento em mulheres HIV+.
Letícia Martins Raposo, Luciane Velasque, Paula Mendes Luz, Ruth Khalili Friedman, Andrea Cytryn, Angela Cristina Vasconcelos de Andrade, Tazio Vanni, Pedro E. A. A. Brasil, Fabio Russomano, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Claudio José Struchiner   +11 more
doaj  

Dermatomyositis as a Paraneoplastic Syndrome Secondary to Carcinoma of Cervix: A Rare Clinical Association

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy characterized by symmetric proximal muscle weakness and distinctive cutaneous manifestations. It is frequently associated with underlying malignancies, making recognition of paraneoplastic features crucial.
Manisha Chapagain, Paras Adhikari, Niranjan Pudasaini, Sabin Poudel, Bijay Timilsina   +4 more
wiley   +1 more source

Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav, Akanksha Kashyap, Lakshay Malhotra, Chethan Rajegowda, Chandra Prakash Prasad   +4 more
wiley   +1 more source

Patient and Caregiver Reported Barriers to Cancer Clinical Trial Participation: A Scoping Review

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background The development of cancer treatments relies on patient participation in clinical trials, yet poor recruitment and retention hinder evidence generation. There exists an urgent need for trial designs that address patient‐identified barriers, informational gaps, and concerns. The goal of this evidence synthesis was to identify patient‐
Sarah Scruton, Chisato Ito, Julia Bohnen, Robin Urquhart, Chiquita Hessels, Summer Konechny, Rosilene Kraft, Randy Thompson, Cheryl Ho, Deirdre Weymann, Yvonne Bombard, Emanuel Krebs, Avram Denburg, Timothy P. Hanna, Howard J. Lim, Saadia Shareen, Dean A. Regier, Samantha Pollard   +17 more
wiley   +1 more source

Uterine malformations and pregnancy losses: is cervical cerclage effective?

, 2000
For many years, we and others have reported the efficacy of cervical cerclage in the prevention of miscarriage in patients with uterine malformations. In this paper the experience of 275 cases collected between 1978 and 1998 is reported.
BAJ G., SURICO, Nicola, ARNULFO A, RIBALDONE R   +3 more
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