Results 51 to 60 of about 110,820 (315)

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Advanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara   +17 more
wiley   +1 more source

Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature

Case Reports in Obstetrics and Gynecology, 2014
Metastasis from various neoplasms to the spleen is very rare and most of the cases are found at autopsy. We report a patient presenting with uterine cervical cancer with splenic metastases.
Shigeki Taga, Mari Sawada, Aya Nagai, Dan Yamamoto, Ryoji Hayase   +4 more
doaj   +1 more source

Survival nomograms after curative neoadjuvant chemotherapy and radical surgery for stage IB2-IIIB cervical cancer [PDF]

, 2018
PURPOSE: The purpose of this study was to develop nomograms for predicting the probability of overall survival (OS) and progression-free survival (PFS) in locally advanced cervical cancer treated with neoadjuvant chemotherapy and radical surgery ...
BENEDETTI PANICI, Pierluigi, DE FELICE, Francesca, Di Pinto, Anna, Marchetti, Claudia, Monti, Marco, Musella, Angela, Muzii, Ludovico, Palaia, Innocenza, Romito, Alessia, Tombolini, Vincenzo   +9 more
core   +1 more source

Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders

Advanced Science, EarlyView.
This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin, Wenjing Liu, Wenjia Lu, Monong Zhao, Lin Cao, Zhiyu Li, Jubo Wang, Xi Xu, Hongxi Wu   +8 more
wiley   +1 more source

Post-conization surveillance in an organized cervical screening program with more than 23,000 years of follow-up

Infectious Agents and Cancer, 2023
Background Cervical cancer is preventable through screening and vaccination against high-risk human papillomavirus (hr-HPV). For a screening program to be successful it is vital that the clinical management and follow-up regime of patients with abnormal ...
Avalon Sundqvist, Johanna Nicklasson, Pernilla Olausson, Christer Borgfeldt   +3 more
doaj   +1 more source

Factors associated with lymphedema after treatment for uterine cervical neoplasms: a systematic review [PDF]

, 2019
Kamila Rodrigues Ferreira, Raquel Boechat de Moura Carvalho, Anke Bergamann, Alberto Bona   +3 more
openaire   +2 more sources

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Reproducibility of lymphovascular space invasion (LVSI) assessment in endometrial cancer [PDF]

, 2019
Aims Lymphovascular space invasion (LVSI) in endometrial cancer (EC) is an important prognostic variable impacting on a patient's individual recurrence risk and adjuvant treatment recommendations.
Bartosch, Carla, Bosse, Tjalling, Genestie, Catherine, Lax, Sigurd F, McCluggage, W Glenn, Nout, Remi, Oosting, Jan, Peters, Elke E M, Singh, Naveena, Smit, Huub C S H, Smit, Vincent T H B M, Van de Vijver, Koen   +11 more
core   +2 more sources

Edge Information‐Augmented Auxiliary Diagnosis Method for Cervical Cancer in Medical Decision‐Making Systems

Advanced Intelligent Systems, EarlyView.
To address the problems of insufficient utilization of multiscale features and inefficient feature sharing between tasks in the model, this study proposes an edge‐enhanced intelligent cervical cancer screening method that achieves feature reuse and improves efficiency by jointly optimizing nucleolus segmentation and lesion classification.
Li Wen, Xiaoqing Zhang, Tingyi Dai, Fangfang Gou, Jia Wu   +4 more
wiley   +1 more source

Trends in cancer mortality in Mexico, 1970-1999 [PDF]

, 2017
Background: Few data on cancer mortality have been published for Mexico over the last few decades. It is therefore of interest to conduct a systematic and updated analysis of cancer mortality in this country. Patients and methods: Age-standardised (world
Bosetti, C., Chatenoud, L., La Vecchia, C., Levi, F., Malvezzi, M., Negri, E., Rodríguez, T.   +6 more
core