Results 51 to 60 of about 13,629 (194)

ENUCLEATION of UTERINE FIBROIDS [PDF]

BMJ, 1898
In the early days of ovarian surgery a tumor thought to be ovarian occasionally turned out to be a pedunculated uterine fibroid and therefore was removed in a similar manner. However, removal of fibroids within the uterus was seldom performed because of the problems of controlling hemorrhage and infection. T . Spencer Wells probably performed the first
openaire   +2 more sources

From prevalence to precision: Integrating phenotype, symptoms, reproductive goals, and treatment in leiomyoma care

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Uterine fibroids (leiomyomas) are present in most women during their reproductive years, yet only a subset becomes clinically meaningful. This disparity poses a central clinical challenge: distinguishing symptoms caused by fibroids from those unrelated to them.
Malcolm G. Munro
wiley   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

Exploring vaginal microbiota–tissue resident stem cell crosstalk: VCAM1/Akt signaling ‐mediated enhancement of regenerative capacity

Interdisciplinary Medicine, EarlyView.
Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim, Eun‐Kyung Min, Choon‐Mi Lee, Kun‐Hee Na, Chan Hum Park, YunJae Jung, Hwa‐Yong Lee   +6 more
wiley   +1 more source

Ultrasound Characteristics of Twisted Pedunculated Subserosal Uterine Leiomyomas: A Case Report and a Systematic Review of the Literature

Journal of Clinical Ultrasound, EarlyView.
Ultrasound may aid in the preoperative diagnosis of torsed pedunculated subserosal uterine leiomyomas (TPSUL), a rare but urgent condition. This study identifies consistent sonographic features across 42 cases, supporting ultrasound as a valuable diagnostic tool and highlighting the need for standardization in TPSUL imaging.
Maddalena Paoli, Pietro Pasquini, Alessandra Pennetta, Ghizzi Chiara, Maria Cristina Scifo, Evaldo Giacomucci   +5 more
wiley   +1 more source

Large submucous uterine fibroid mass

Ibom Medical Journal
Background: Uterine fibroids or leiomyomas, are common benign tumors originating from the smooth muscle cells of the uterus. While typically asymptomatic, large submucous fibroids can cause significant clinical manifestations, including abnormal uterine
Obiozor AA, Obiozor CG
doaj   +1 more source

CLINICAL AND MORPHOLOGICAL CHARACTERISTICS AND PROGNOSTIC SIGNIFICANCE OF THE CONTENTS OF PD-ECGF, TGF-β, KI67 IN ENDOMETRIUM AT LARGE UTERINE LEIOMYOMA

Клиническая практика, 2016
The endometrium may be the most convenient object of forecasting the development of the large uterine fibroid, as the object is available in the diagnosis of diseases of the uterus, changes in its cytokine profile linked with the growth of uterine ...
S I Askolskaya, E A Kogan, Yu V Popov, M A Solomakhina, N M Fayzullina   +4 more
doaj   +1 more source

Extracellular matrix and Hippo signaling as therapeutic targets of antifibrotic compounds for uterine fibroids

Clinical and Translational Medicine, 2021
Background Uterine fibroids are highly prevalent, collagen‐rich, mechanically stiff, fibrotic tumors for which new therapeutic options are needed. Increased extracellular matrix (ECM) stiffness activates mechanical signaling and Hippo/YAP promoting ...
Md Soriful Islam, Sadia Afrin, Bhuchitra Singh, Friederike L. Jayes, Joshua T. Brennan, Mostafa A. Borahay, Phyllis C. Leppert, James H. Segars   +7 more
doaj   +1 more source

Concordance of Preoperative Transvaginal Ultrasound and Intraoperative Findings in Fibroid Ablation Using Transcervical Ultrasound

Journal of Ultrasound in Medicine, EarlyView.
Objective To evaluate concordance between the number of uterine fibroids deemed clinically significant on preoperative transvaginal sonography (TVS) and the number of fibroids treated intraoperatively during transcervical radiofrequency ablation (RFA) under intrauterine ultrasound guidance.
Philip G. Hepp, Markus Fleisch, Ines Beyer   +2 more
wiley   +1 more source

The impact of uterine artery embolisation on fibroid volume at 436 months in women with symptomatic fibroids at a tertiarylevel hospital

South African Journal of Obstetrics and Gynaecology, 2017
Background. Symptomatic uterine fibroids have a significant impact on women’s health. Surgical intervention (myomectomy and hysterectomy) has been the mainstay of treatment.
Z Abdool, R T Mogakane, S Ahmad, H M Swanepoel   +3 more
doaj   +1 more source