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ENUCLEATION of UTERINE FIBROIDS [PDF]
BMJ, 1898 In the early days of ovarian surgery a tumor thought to be ovarian occasionally turned out to be a pedunculated uterine fibroid and therefore was removed in a similar manner. However, removal of fibroids within the uterus was seldom performed because of the problems of controlling hemorrhage and infection. T . Spencer Wells probably performed the first
openaire +2 more sources
Impact of Contraception on Uterine Fibroids
Medicina, 2021 Background and Objectives: Uterine fibroids develop in 25–40% of women of childbearing age; however, there are discrepancies resulting from population and socioeconomic differences. The pathogenesis of fibroids is not clear.
Katarzyna Kwas +6 more
semanticscholar +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Uterine fibroids (leiomyomas) are present in most women during their reproductive years, yet only a subset becomes clinically meaningful. This disparity poses a central clinical challenge: distinguishing symptoms caused by fibroids from those unrelated to them.
Malcolm G. Munro
wiley +1 more source
Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids.
New England Journal of Medicine, 2020 BACKGROUND Uterine fibroids are hormone-responsive neoplasms that are associated with heavy menstrual bleeding. Elagolix, an oral gonadotropin-releasing hormone antagonist resulting in rapid, reversible suppression of ovarian sex hormones, may reduce ...
W. Schlaff +20 more
semanticscholar +1 more source
Interdisciplinary Medicine, EarlyView.This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley +1 more source
Interdisciplinary Medicine, EarlyView.Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim +6 more
wiley +1 more source
Journal of Clinical Ultrasound, EarlyView.Ultrasound may aid in the preoperative diagnosis of torsed pedunculated subserosal uterine leiomyomas (TPSUL), a rare but urgent condition. This study identifies consistent sonographic features across 42 cases, supporting ultrasound as a valuable diagnostic tool and highlighting the need for standardization in TPSUL imaging.
Maddalena Paoli +5 more
wiley +1 more source
Uterine-Artery Embolization or Myomectomy for Uterine Fibroids.
New England Journal of Medicine, 2020 BACKGROUND Uterine fibroids, the most common type of tumor among women of reproductive age, are associated with heavy menstrual bleeding, abdominal discomfort, subfertility, and a reduced quality of life.
I. Manyonda +10 more
semanticscholar +1 more source
Journal of Ultrasound in Medicine, EarlyView.Objective To evaluate concordance between the number of uterine fibroids deemed clinically significant on preoperative transvaginal sonography (TVS) and the number of fibroids treated intraoperatively during transcervical radiofrequency ablation (RFA) under intrauterine ultrasound guidance.
Philip G. Hepp +2 more
wiley +1 more source