Results 61 to 70 of about 6,613 (273)

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Insights into the role of PGF2α in canine periparturient myometrium

Frontiers in Physiology
Parturition in dogs is subjected to complex hormonal regulation, with the involvement of prostaglandin F2α (PGF2α) still not fully understood. To investigate uterine inertia (UI), the most prevalent maternal reason for dystocia in the bitch, a better ...
Carolin Jungmann, Signe Dyhrberg Haubuff, Eva-Maria Packeiser, Hanna Körber, Iris Margaret Reichler, Orsolya Balogh, Orsolya Balogh, Gemma Mazzuoli-Weber, Sandra Goericke-Pesch   +8 more
doaj   +1 more source

Second-Stage Labor Care: Challenges in Spontaneous Bearing Down [PDF]

, 2009
Substantial scientific evidence supports spontaneous maternal bearing down for its associated maternal and fetal physiologic benefits. Imposing specific directions for Valsalva pushing does not result in optimal outcomes but continues to be widely used ...
Hanson, Lisa
core   +1 more source

Long‐term association of physical activity with survival by primary cancer treatment in endometrial cancer: The Alberta Endometrial Cancer Cohort Study

International Journal of Cancer, EarlyView.
What's New? Accumulating evidence suggests a beneficial role of physical activity in cancer. However, it is unclear whether associations between physical activity and cancer outcomes vary by cancer treatment. Based on more than 16 years of follow‐up data from a cohort of endometrial cancer survivors, this study reveals that associations between ...
Minsuk Oh, Ki‐Yong An, Dong Hoon Lee, Renée L. Kokts‐Porietis, Linda S. Cook, Christine M. Friedenreich, Justin Y. Jeon, Kerry S. Courneya   +7 more
wiley   +1 more source

Acute hypothalamic suppression significantly affects trabecular bone but not cortical bone following recovery and ovariectomy surgery in a rat model [PDF]

PeerJ, 2016
Background. Osteoporosis is “a pediatric disease with geriatric consequences.” Bone morphology and tissue quality co-adapt during ontogeny for sufficient bone stiffness.
Vanessa R. Yingling, Kathryn A. Mitchell, Megan Lunny   +2 more
doaj   +2 more sources

International breeder inquiry into the reproduction of the English bulldog [PDF]

, 2013
Dystocia may occur in all dog breeds, but the English bulldog is predisposed because of its conformation and specific problems such as anasarca pups. In this study, the frequency of abnormal pups and breeding problems in English bulldogs was investigated
Berghmans, E, Rijsselaere, Tom, Van Soom, Ann, Wydooghe, Eline   +3 more
core   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Dystocia in sheep and goats: outcome and fertility following surgical and non-surgical management [PDF]

Macedonian Veterinary Review, 2017
Cesarean section is a life-saving surgical procedure usually undertaken in sheep and goats that fail to deliver vaginally (dystocia). Unfortunately, there are no recent review articles in literature that summarize the results of published case reports ...
Zuhair Bani Ismail
doaj   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source