Results 181 to 190 of about 19,375 (225)
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PTPN22 and uterine leiomyomas

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2015
It has been suggested that the development of uterine leiomyomas is positively influenced by an immune system in a chronically inflammatory state and that a lower level of regulating T cell (Treg cells) would play a central role. Since it has been suggested that the W620 variant of protein tyrosine phosphatase non-receptor type 22 (PTPN22) decreases ...
Fulvia, Gloria-Bottini   +4 more
openaire   +2 more sources

The Frequency of Uterine Leiomyomas

American Journal of Clinical Pathology, 1990
As a leading cause of hysterectomy in premenopausal women. uterine leiomyomas are a major public health problem. However, very little work has been done on their epidemiology. Indeed, their true frequency has never been established using systematic and meticulous methods.
S F, Cramer, A, Patel
openaire   +2 more sources

Uterine Leiomyoma in a Sheep

Reproduction in Domestic Animals, 2009
Leiomyomas are benign tumours, which are frequently found in animal species. However, the presence of leiomyomas in domestic ruminants has been rarely reported, especially in sheep. This report describes the pathological and immunohistochemical characteristics of a leiomyoma in the uterine body of a sheep and discusses the different aetiological causes.
J M, Corpa, C M, Martínez
openaire   +2 more sources

Uterine Leiomyoma

Annals of the New York Academy of Sciences, 2001
Abstract: Many risk factors have been identified as having either a protective or a negative effect on the development of fibroids, but due to methodological issues and a lack of long‐term studies, the exact effect of these factors is ambiguous. In similar dispute is the proper treatment of fibroids. Recent technological advances have introduced newer,
M E, Moorehead, C J, Conard
openaire   +2 more sources

Uterine leiomyoma cytogenetics

Genes, Chromosomes and Cancer, 1990
AbstractUterine leiomyoma—a benign smooth muscle tumor—has recently been found to contain tumor‐specific chromosome aberrations. Although only normal karyotypes were detected in 50 to 80% of cytogenetically investigated tumors, 104 leiomyomas with karyotypic aberrations have already been reported.
M, Nibert, S, Heim
openaire   +2 more sources

Sarcoidosis in a uterine leiomyoma

International Journal of Gynecology & Obstetrics, 1995
AbstractSarcoidosis is a granulomatous condition of unknown etiology. Though the lung and lymph nodes are most commonly involved, other organs may also be affected. Involvement of the female reproductive system is very uncommon and usually has been found in the endometrium or myometrium.
A W, Menzin   +4 more
openaire   +2 more sources

Characterization of the uterine leiomyoma microRNAome by deep sequencing

open access: yesGenomics, 2012
MicroRNAs (miRNAs) are a class of small non-coding RNAs, which are negative regulators of gene expression. Many genes in human uterine leiomyoma (ULM) are aberrantly expressed and in some cases this can be due to dysregulation of miRNAs.
Ivan Minkov   +2 more
exaly   +2 more sources

Pathophysiology of uterine leiomyomas

Biochemistry and Cell Biology, 1992
Uterine leiomyomas is the most common benign neoplasia in women, one of the most frequent causes of infertility in reproductive years, and the leading cause for hysterectomy. The pathophysiology of uterine leiomyomas is uncertain. Therefore, therapeutic approaches have been primarily empirical. It is now well documented that growth factors control the
openaire   +2 more sources

Uterine Leiomyomas and Reproduction

Obstetrics & Gynecology
There is a prevailing opinion by gynecologists, much of it based on expert opinion or anecdotal evidence, that myomas are detrimental to pregnancy. Newer data challenge much of this dogma, but incorrect assumptions remain. Although not impeccable, multiple data address the correlation between myomas and reproduction, and some emerging evidence ...
openaire   +2 more sources

Uterine Leiomyoma

Mayo Clinic Proceedings, 2019
J Kenneth, Schoolmeester   +1 more
openaire   +2 more sources

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