Results 71 to 80 of about 19,375 (225)

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

Cell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo, Tianxiang Liu, Runling Ren, Na Li, Wenwen Zhang, Jingwen Si, Yongjun Piao, Yuanjing Hu   +7 more
wiley   +1 more source

Hypercalcemia: An Unusual Manifestation of Uterine Leiomyoma

, 2013
We present a case of hypercalcemia in a 79-year-old female likely secondary to uterine leiomyoma. To the best of our knowledge, hypercalcemia due to a benign tumor has only been described in five cases.
Amarinder Singh Garcha, Sujith Cherian, Apurv Khanna, Purva Gumaste   +3 more
core   +1 more source

Cutaneous Leiomyosarcoma of the Skin: An Updated Review of Epidemiology, Pathogenesis, and Management

International Journal of Dermatology, EarlyView.
This review provides an update on the epidemiology, pathogenesis, and clinical/histologic features of cutaneous leiomyosarcoma. Prognostic factors (e.g., depth of tumor involvement, grade, etc.) that can facilitate risk stratification are also discussed, as are treatment approaches for this rare malignancy.
Tejas P. Joshi, Natalie Garcia, Malak Husseinali, Nabeeha Engineer, Ikue Shimizu   +4 more
wiley   +1 more source

Evaluation of vitamin D receptor expression in uterine leiomyoma and nonneoplastic myometrial tissue: a cross‐sectional controlled study

Reproductive Biology and Endocrinology, 2021
Background Uterine myomas are the most frequent benign solid pelvic tumors in women of reproductive age. At present, uterine myomas are the most common indication for hysterectomy because of the morbidity they cause, including intense bleeding ...
Maria Simone Oliveira Lima, Benedito Borges da Silva, Menandro Lima de Medeiros, Alesse Ribeiro dos Santos, Emerson Davi do Nascimento Brazil, Walberto Monteiro Neiva Eulálio Filho, Jerusia Oliveira Ibiapina, Antônio Gilberto Albuquerque Brito, Pedro Vitor Lopes Costa   +8 more
doaj   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

A benign uterine leiomyoma with disturbing appearance

, 2019
Herein, we described a 53-year-old woman who underwent laparoscopic uterine myomectomy. The cut surface of the leiomyoma showed a grain appearance, instead of a whorled feature. The disturbing appearance was an unexpected surprise to the surgeon.
Xiaoyang Fei, Hao Chen, Wenchao Sun, Lingna Chen   +3 more
core   +1 more source

Environmental exposure and risk of uterine leiomyoma: an epidemiologic survey [PDF]

, 2020
. -AIM: The present study was undertaken to explore the relationship between environmental exposure and risk of uterine leiomyoma in women using an epidemiologic survey.
J Xu, Y L Cai, Q Xu, Ph.D; Yang Shen, Y Shen, M L Ren   +5 more
core  

Cervical Metastasis From Primary Breast Carcinoma: A Case Report and Review of Extragenital Tumors Involving the Uterine Cervix

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cervical metastases from breast carcinoma should be considered in the differential diagnosis of uterine lesions in patients with prior breast cancer. Re‐biopsy is essential to detect receptor discordance (ER/PR up to 29%) and guide therapy. GCDFP‐15, mammaglobin, and GATA3 confirm mammary origin.
Mario Assenza, Adele Zappalà, Armando Nallbani, Jacopo Wabersich   +3 more
wiley   +1 more source

Incidental Rectus Abdominis Leiomyoma Discovered During Emergency Cesarean Section: A Rare Case Report From Northern Tanzania

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Uterine fibroids, also referred to as leiomyomas, are benign uterine tumors with a lifetime prevalence of approximately 75% depending on race, age, and a variety of genetic and environmental factors. Extra‐uterine leiomyomas are uncommon, and their occurrence within the rectus abdominis muscle is exceptionally rare.
Ibrahim Salum, John Lugata, Kimberly R. Sladek, Augustino Mayokolo, Anthony Ramadhan, Living Morewa, Kenneth Bagandanshwa, Joachim Magoma, Alex Mremi, Thomas Kakumbi   +9 more
wiley   +1 more source

Bioequivalence of a Fixed‐Dose Combination of Relugolix, Estradiol, and Norethindrone Acetate: An Open‐Label, Randomized, Fully Replicate Crossover Study in Healthy Postmenopausal Women Under Fasting Conditions

Clinical Pharmacology in Drug Development, Volume 15, Issue 6, June 2026.
Abstract Uterine fibroids are the most common benign gynecological tumors, often causing heavy menstrual bleeding (HMB), anemia, and impaired quality of life. A fixed‐dose combination (FDC) of relugolix (40 mg), estradiol (1 mg), and norethindrone acetate (0.5 mg) was developed to address these limitations.
Ravi Kotadia, Sudershan Kumar, Arshad Khuroo, Shruti Dharmadhikari, Pradeep Shahi, Goru N. V. S. Satya Narayana, Simrit Reyar   +6 more
wiley   +1 more source