Results 91 to 100 of about 690,694 (375)

Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review

Radiology Case Reports, 2021
Herlyn-Werner-Wunderlich syndrome, is a rare urogenital congenital anomaly. Coexisting Mullerian ducts anomalies and ovarian neoplasms are rarely reported.
Johara AlMulhim, MD, Mohannad Rasheed AlRasheed, MD   +1 more
doaj   +1 more source

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

Advanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang, Jian Qi, Jialiang Wang, Zhipeng Wang, Yongguang Wang, Zongtao Hu, Ao Xu, Bo Hong, Hongzhi Wang   +8 more
wiley   +1 more source

Presence of histopathological premalignant lesions and infection caused by high-risk genotypes of human papillomavirus in patients with suspicious cytological and colposcopy results: A prospective study [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. In patients with premalignant cervical lesions, human papillomavirus (HPV) infection, at any moment, may be spontaneously eliminated, or may persist or transform cervical epithelium from a lower to a higher degree.
Golubović Mileta, Lopičić Milena, Terzić Nataša, Đurović Marija, Mugoša Boban, Mijović Gordana   +5 more
doaj   +1 more source

Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study. [PDF]

, 2013
BackgroundLobular endocervical glandular hyperplasia (LEGH) is a rare lesion of the uterine cervix. It has been proposed that LEGH may represent a precursor lesion to a group of mucinous adenocarcinoma with gastric phenotype (GA) that is independent of ...
Carter, R, Darcy, KM, Hatae, M, Kauderer, J, Liao, SY, Nagao, S, Rodgers, WH, Stanbridge, EJ, Susumu, N, Walker, JL   +9 more
core   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

Oviductal and uterine leiomyomata in mares [PDF]

, 2013
This paper describes a case of a sessile uterine leiomyoma in a 17-year-old chronic infertile Selle Francais mare. The mass was removed by transendoscopic electrocoagulation.
Chiers, Koen, de Vries, C, Govaere, Jan, Hoogewijs, Maarten, Leemans, Bart, Nelis, Hilde   +5 more
core  

Mechanisms and Pathophysiological Significance of Insulin Resistance in Offspring With Intrauterine Growth Restriction Mediated by Hepatic GR/miR‐1224 Programming

Advanced Science, EarlyView.
This work found that early‐stage insulin sensitization but late‐stage insulin resistance in prenatal caffeine exposure (PCE)‐ induced intrauterine growth restriction (IUGR) offspring may be related to the hepatic AGEs accumulation via intrauterine GR/miR‐1224 programming by glucocorticoids.
Yongguo Dai, Xiaoling Guo, Pengxia Yu, Dingmei Zhang, Hao Kou, Hui Wang   +5 more
wiley   +1 more source

Clear Cell Adenocarcinoma of Cervix: Radical Trachelectomy to Preserve the Fertility [PDF]

, 2016
Carcinoma of the uterine cervix is a common gynecologic malignant neoplasm all over the world. The most common histological type of malignant cervical neoplasms is squamous cell carcinoma [1,2].
Herraiz Roda, José Luis, Llueca, Antoni, Maazouzi, Yasmine, Medina, Carmen, Piquer Simó, Dolors   +4 more
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Survival analysis of patients with rare tumors of the uterine corpus – carcinosarcoma [PDF]

Vojnosanitetski Pregled
Background/Aim. Uterine carcinosarcoma (UCS), formerly known as malignant mixed Müllerian tumor, is a rare, aggressive malignancy of the female genital tract.
Stevanović Nemanja, Mandić Aljoša, Maričić Slobodan, Nadj Gabriel Stefan, Maksimović Tamara, Stanulović Nevena, Čančar Vladimir, Rodić Milan   +7 more
doaj   +1 more source