Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]
, 2014 Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa +6 more
core +1 more source
Gynecologic Oncology Reports, 2023 In depth molecular studies are constantly expanding our understanding and refining the classification of gynecological neoplasms. NTRK rearranged spindle cell neoplasms of the lower genital tract are an emerging entity, of particular interest due to ...
Marco M. Bühler +4 more
doaj +1 more source
Association of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and high-grade undifferentiated endometrial sarcoma. a case report [PDF]
, 2017 Endometriosis is a chronic disease that affects women of reproductive age. Malignant transformation in endometriosis is considered to be an unusual event, only occurring in 0.7-0.1% of cases.
Caserta, D. +3 more
core +1 more source
Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience. [PDF]
, 2016 BackgroundHER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti ...
Apple, Sophia K +5 more
core +2 more sources
BMC Women's Health, 2021 Background Uterine rhabdomyosarcoma is an extremely rare malignant tumor that usually affects young women and has a poor prognosis. Case presentation A 19-year-old nulliparous woman presented to the emergency department under sedation due to seizures ...
Hongfa Peng +2 more
doaj +1 more source
Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat [PDF]
, 2017 Case summary A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE).
Fowkes, R C +8 more
core +2 more sources
Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities [PDF]
, 2015 Background : Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are detectable in 10% to 15% of women seeking treatment for ...
Bosteels, Jan +5 more
core +5 more sources
Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. [PDF]
, 2018 Adenomatoid tumors are the most common neoplasm of the epididymis, and histologically similar adenomatoid tumors also commonly arise in the uterus and fallopian tube.
Bastian, Boris C +13 more
core +1 more source
Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplifications
The Journal of Pathology: Clinical Research, 2020 Recently a novel subtype of endometrial stromal sarcoma (ESS) defined by recurrent genomic alterations involving BCOR has been described (HGESS‐BCOR). We identified a case of HGESS‐BCOR with a ZC3H7B‐BCOR gene fusion, which harbored an amplification of ...
Felix KF Kommoss +15 more
doaj +1 more source