Results 191 to 200 of about 43,595 (291)

Effect of Targeted Aspirin Administration Based on First Trimester Combined Screening for Preeclampsia on Preterm Birth: An Interrupted Time Series Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 8, Page 1547-1552, July 2026.
ABSTRACT Objectives To assess the effect of an aspirin intervention program on preterm birth (PTB) rates in women identified as high‐risk for preterm preeclampsia in the first‐trimester screening. Design This is a retrospective study evaluating the impact of the intervention program on preterm birth using interrupted time series analysis (ITSA) with an
Monica Minopoli   +5 more
wiley   +1 more source

Clinical Characteristics Associated With Very Preterm Delivery Despite Transabdominal Cerclage: A Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 8, Page 1553-1560, July 2026.
ABSTRACT Objective To identify factors associated with unsuccessful transabdominal cerclage (TAC) insertion, defined as delivery before 32 weeks, including maternal demographics, preterm birth risk factors, operative details (laparoscopic or open, pre‐pregnancy or during pregnancy) and subsequent cervical length.
Laura van der Krogt   +3 more
wiley   +1 more source

Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang   +15 more
wiley   +1 more source

Novel MYL1 Intron Variant With Expanded Phenotype

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1378-1383, June 2026.
ABSTRACT Congenital myopathy‐14 (CMYO14) is an ultrarare autosomal recessive disorder caused by biallelic variants in MYL1, with only four patients reported to date. We describe what is likely the fifth reported patient, a neonate with severe hypotonia, respiratory insufficiency, and skeletal anomalies showing distinct histological changes of skeletal ...
Maria Barington   +7 more
wiley   +1 more source

Successful Treatment of Recurrent Hematometra With Ethanol Sclerotherapy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT To our knowledge, this case report is the first to show that ethanol sclerotherapy can safely and effectively resolve recurrent hematometra caused by postradiotherapy stenosis and recurrent cervical cancer. For patients with poor overall condition in whom cervical drainage is not feasible, this minimally invasive approach may serve as a ...
Kojiro Tanabe   +3 more
wiley   +1 more source

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