Results 91 to 100 of about 211,160 (222)

HierAnom‐Path: Zero‐Shot Rare Cancer Detection in Histopathology via Hierarchical Foundation Model Adaptation

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah, Mohanad Sameer Jabbar, Saif H. Alwaeli, Noor Ayesha, Mohamed Babiker A. Mohamed, Muhammad I. Khan   +5 more
wiley   +1 more source

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

International Journal of Cancer, Volume 159, Issue 9, Page 2290-2299, 1 November 2026.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel, Theresa Lowinus, Patrick Metzger, Rebecca Czurda, Vincent Schipperges, Ulrike Paul, Alessandra Rünger, Julian Kött, Isabel Heidrich, Saskia Lehr, Julia Kühn, Heiko Becker, Cornelius Miething, Martin Werner, Silke Laßmann, Justus Duyster, Tilman Brummer, Ronald Simon, Winfried Alsdorf, Maximilian Christopeit, Carsten Bokemeyer, Kilian Eyerich, Stefan W. Schneider, David Rafei, Melanie Börries, Frank Meiss, Christoffer Gebhardt   +26 more
wiley   +1 more source

HDlive Flow Silhouette Mode for the Diagnosis of Uterine Sarcoma

, 2016
We present our initial experience of using the HDlive Flow silhouette mode to construct an image of uterine sarcoma. Two-dimensional sonography showed a heterogeneous uterine mass with central, irregular cystic areas.
Megumi Ito
core   +1 more source

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy [PDF]

, 2014
Abnormal uterine activity in pregnancy causes a range of important clinical disorders, including preterm birth, dysfunctional labour and post-partum haemorrhage.
Dale, T, Nan Lin, Brown, Pamela, England, Sarah, Pamela Brown, Jeff Jerman, McCavera, Samantha, Rand, DA, Tickle, D, Kettleborough, Catherine, McCavera, S, Brosens, Jan, Taggart, MJ, Chan, YW, Trezise, Derek J., Catherine Kettleborough, Manu Vatish, Denton, JS, Jerod S Denton, van den Berg, HA, Siobhan Quenby, Atia, Jolene, Cara Rada, England, Sarah K, Rada, C, Rada, Cara, Rand, David A., Shmygol, A, Catalano, R, Vatish, M, Brown, P, van den Berg, Hugo A., Dale, Timothy, David A Rand, Michael J Taggart, Kettleborough, C, McCloskey, C., Lin, Nan, McCloskey, C, Bailey, Elizabeth H., Chan, Yi-Wah, Vatish, Manu, Jerman, J, Andrew M Blanks, Sarah K England, Tickle, David, Berg, Hugo van den, Kanumilli, S, Shmygol, Anatoly, England, Sarah K., Quenby, S, Chan, Y-W, Srinivasan Kanumilli, Steve Thornton, Conor McCloskey, Timothy Dale, Zhang, J, Kanumilli, Srinivasan, David Tickle, Catalano, Roberto D., Atia, J, Yi‐Wah Chan, Jan J Brosens, England, S., Trezise, Derek, Paul Wright, Trezise, DJ, Jie Zhang, Roberto Catalano, Quenby, Siobhan, Bailey, Elizabeth, Derek J Trezise, Brosens, Jan J., McCloskey, Conor, Jerman, Jeff, England, SK, Denton, Jerod S., Zhang, Jie, Brosens, JJ, et al,, Wright, P, Thornton, S, Thornton, Steven, Hugo A van den Berg, Jolene Atia, Taggart, Michael J., Blanks, Andrew M., van den Berg, H. A., Thornton, Steve, Catalano, Roberto, Blanks, AM, Samantha McCavera, Rand, D. A., Blanks, Andrew, Denton, Jerod, Lin, N, Taggart, Michael, Wright, Paul, Bailey, E, Elizabeth Bailey, Anatoly Shmygol   +100 more
core   +1 more source

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in seven patients with peritoneal sarcomatosis from uterine sarcoma

Clinical Case Reports, 2018
Key Clinical Message Peritoneal sarcomatosis from uterine sarcoma is a rare disease with no effective treatment and poor prognosis. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has successful results in peritoneal ...
Armando Sardi, Carlos A. Muñoz‐Zuluaga, Michelle Sittig, Teresa Diaz‐Montes   +3 more
doaj   +1 more source

CCNE1: A Cell Cycle Regulator That Influences Tumor Progression

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACTCyclin E1 (CCNE1), a pivotal member of the cyclin family, governs the G1/S phase transition of the cell cycle by binding to and activating cyclin‐dependent kinase 2 (CDK2), thereby initiating DNA replication and driving S‐phase entry. In a broad spectrum of human malignancies—including breast, ovarian, gastric, and non‐small cell lung cancers ...
Liang Yan, Siyi Liu, Yanling Li, Qian He, Chen Long, Ning Tang, Yanhong Zhou   +6 more
wiley   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

Uterine Endoplasmic Reticulum Stress and Its Unfolded Protein Response May Regulate Caspase 3 Activation in the Pregnant Mouse Uterus [PDF]

, 2013
We have previously proposed that uterine caspase-3 may modulate uterine contractility in a gestationally regulated fashion. The objective of this study was to determine the mechanism by which uterine caspase-3 is activated and consequently controlled in ...
Subedi, Kalpana, Jennifer C. Condon, Chandrashekara Kyathanahalli, Kalpana Subedi, Lydon, John P., Arvind Suresh, Kyathanahalli, Chandrashekara, Condon, Jennifer C., Jeyasuria, Pancharatnam, Pancharatnam Jeyasuria, Rashekara Kyathanahalli, Jennifer C Condon, Suresh, Arvind   +12 more
core   +2 more sources

Mapping Mutations and Signaling Network Interactions to Guide Precision Therapy in Gallbladder Cancer

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav, Akanksha Kashyap, Lakshay Malhotra, Chethan Rajegowda, Chandra Prakash Prasad   +4 more
wiley   +1 more source

Incidence of Gynecological Cancers Is Rising in Northern Iran: A Population‐Based, Serial Cross‐Sectional Joinpoint Regression Study

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Gynecological cancers are a major global health burden, with ovarian, uterine, and cervical cancers being the most common types. Despite rising national incidence rates, recent comprehensive data for Gilan Province remain limited.
Mohammad Amouzadeh‐Lichahi, Sahand Karimzadhagh, Nooshin Zaresharifi, Azadeh Jafari, Paridokht Karimian, Maryam Jafari, Gholamreza Sadeghi, Mohammad Ali Yazdanipour   +7 more
wiley   +1 more source