Results 121 to 130 of about 569,732 (406)

"INVERSION OF THE UTERUS." [PDF]

The Lancet, 1885
n ...
openaire   +3 more sources

HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF‐κB/SOD2 Signaling Pathway

Advanced Science, EarlyView.
HIGD1A maintains redox homeostasis in granulosa cells by modulating SOD2‐mediated dismutation of superoxide into H2O2, which is cleared by CAT and GPX enzymes. However, reduced HIGD1A activates the NF‐κB pathway and upregulates SOD2, leading to intracellular H2O2 accumulation due to impaired clearance.
Huiying Li, Siying Cai, Hongbei Mu, Tianli Chang, Xiaofei Wang, Tianyu Tang, Tengyun Dong, Yu Zhang, Ling Zhang, Huaibiao Li, Liquan Zhou, Wenpei Xiang   +11 more
wiley   +1 more source

Uterine prostaglandin DP receptor-induced upon implantation contributes to decidualization together with EP4 receptor

Journal of Lipid Research
To investigate the yet-unknown roles of prostaglandins (PGs) in the uterus, we analyzed the expression of various PG receptors in the uterus. We found that three types of Gs-coupled PG receptors, DP, EP2, and EP4, were expressed in luminal epithelial ...
Risa Sakamoto, Takuji Fujiwara, Yuko Kawano, Shizu Aikawa, Tomoaki Inazumi, On Nakayama, Yukiko Kawasaki-Shirata, Miho Hashimoto-Iwasaki, Toshiko Sugimoto, Soken Tsuchiya, Satohiro Nakao, Toru Takeo, Yasushi Hirota, Yukihiko Sugimoto   +13 more
doaj   +1 more source

AffinityNet: semi-supervised few-shot learning for disease type prediction

, 2018
While deep learning has achieved great success in computer vision and many other fields, currently it does not work very well on patient genomic data with the "big p, small N" problem (i.e., a relatively small number of samples with high-dimensional ...
Ma, Tianle, Zhang, Aidong
core   +1 more source

Didelphys Uterus: A Case Report and Review of the Literature

Case Reports in Obstetrics and Gynecology, 2015
Background. Mullerian duct anomalies (MDAs) are congenital defects of the female genital system that arise from abnormal embryological development of the Mullerian ducts.
S. Rezai, Pameela Bisram, Isamarie Lora Alcantara, R. Upadhyay, Carla Lara, Malvina Elmadjian   +5 more
semanticscholar   +1 more source

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

Advanced Science, EarlyView.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao, Pu Xing, Hao Hao, Jiangbo Chen, Lin Song, Yifan Hou, Xinying Yang, Kai Weng, Jie Chen, Pin Gao, Tongkun Song, Hong Yang, Tianqi Liu, Yumeng Ran, Bo Chen, Wei Zhao, Jiabo Di, Zaozao Wang, Jun Zhang, Xiangqian Su, Beihai Jiang   +20 more
wiley   +1 more source

Endometriosis: 10 keys points for MRI [PDF]

, 2015
Endometriosis is a chronic disease and a clinical problem in women of fertile age, with a high impact on quality of life, work productivity and health care management.
ANASTASI, Emanuela, BALLESIO, Laura, BERNARDO, SILVIA, FUGGETTA, ELIANA, GIANCOTTI, Antonella, MANGANARO, Lucia, PORPORA, Maria Grazia, SALDARI, MATTEO, SOLLAZZO, PAOLO, VINCI , VALERIA   +9 more
core   +1 more source

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

Advanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu, Peikang Zhang, Zhen Xiong, Yufei Lan, Hui Guo, Runyuan Wu, Cunzhen Li, Hongzhe Fan, Ying Du, Xiaoxiao Zhu, Dongdong Fan, Zhonglong Wang, Yong Tian, Zusen Fan   +13 more
wiley   +1 more source

Fertility preservation in gynaecologic cancers [PDF]

, 2018
Due to substantial improvement in the diagnosis and treatment of gynaecologic cancers, a better understanding of patient care needs to be revised. We reviewed the literature related to fertility preservation strategies in gynaecological cancer and ...
De Felice, Francesca, Di Pinto, Anna, Marchetti, Claudia, Musella, Angela, Muzii, Ludovico, Palaia, Innocenza, Panici, Pierluigi Benedetti, Porpora, Maria Grazia, Tomao, Federica, Tombolini, Vincenzo   +9 more
core   +1 more source

Extracellular Vesicles in Luminal Fluid of the Ovine Uterus

PLoS ONE, 2014
Microvesicles and exosomes are nanoparticles released from cells and can contain small RNAs, mRNA and proteins that affect cells at distant sites. In sheep, endogenous beta retroviruses (enJSRVs) are expressed in the endometrial epithelia of the uterus ...
G. Burns, K. Brooks, M. Wildung, R. Navakanitworakul, L. Christenson, T. Spencer   +5 more
semanticscholar   +1 more source