Results 161 to 170 of about 371,169 (260)

Non‐Porous Hydrogel Scaffolds for Locoregional Chemotherapy: A One‐Pot Synthesis Approach

open access: yesMacromolecular Materials and Engineering, EarlyView.
This hydrogel scaffold with tunable mechanical, water retention, degradation, and drug release properties is obtained by polymerizing the hydrophilic OEGMEMA monomer in the presence of PLGA and DOX under concentrated conditions. Its non‐porous structure provides diffusion‐based drug release, while extended drug release is possible by incorporating PLGA.
Sadik Kaga, Gizem Fatma Erguner
wiley   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Comparison of secondary radiation dose between pencil beam scanning and scattered delivery for proton and VHEE radiotherapy

open access: yesMedical Physics, EarlyView.
Abstract Background Very high‐energy electrons (VHEEs) in radiotherapy may offer several potential advantages over conventional electron beams and other techniques, for example, the fact that they can be used at ultra‐high dose rates (UHDRs), therefore enabling FLASH radiotherapy.
Maria Grazia Ronga   +7 more
wiley   +1 more source

Quantifying multi‐institutional ADC measurement variability of 1.5 T MR‐Linacs: A phantom and in vivo study

open access: yesMedical Physics, EarlyView.
Abstract Background Diffusion‐weighted imaging (DWI), a quantitative magnetic resonance imaging (qMRI) technique, has the potential to aid in disease characterization and treatment response monitoring. MR‐Linacs (MRLs) enable simultaneous DWI acquisitions during radiotherapy, uniquely aiding in the collection of large‐scale datasets for imaging ...
Madeline E. Carr   +11 more
wiley   +1 more source

Cystathionine gamma‐lyase‐mediated hypoxia inducible factor 1‐alpha expression drives clear cell ovarian cancer progression

open access: yesThe Journal of Pathology, EarlyView.
Abstract Clear cell ovarian cancer (CCOC) is the second most common ovarian cancer subtype, accounting for 5%–11% of ovarian cancers in North America. Late‐stage CCOC is associated with a worse prognosis compared to other ovarian cancer histotypes, a challenge that has seen limited progress in recent decades.
Amal M EL‐Naggar   +27 more
wiley   +1 more source

Whole Abdominal Radiotherapy Is Tolerable and Effective in Children and Young Adults With Intra‐Abdominal Sarcoma: A Canadian Sarcoma Research and Clinical Collaboration (CanSaRCC) Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Whole abdominal radiotherapy (WART) is utilized in children, adolescents, and young adults with intra‐abdominal sarcoma, but efficacy and toxicity are uncertain. Methods Sarcoma patients diagnosed at ≤39 years of age between 1998 and 2023 who received WART were identified from a national registry.
Rebecca J. Deyell   +12 more
wiley   +1 more source

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