Results 41 to 50 of about 211,267 (256)

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Vascularized composite allograft deceased donation in the United States

Frontiers in Transplantation
Vascularized composite allograft (VCA) transplantation represents a significant advancement in reconstructive surgery and offers hope to individuals who experienced congenital disorders or severe tissue injuries to restore physical appearance, function ...
Wida S. Cherikh, Samantha M. Noreen, Alexandra Lewis, Sarah E. Booker, Jesse Howell, Erin M. Schnellinger, Jennifer L. Wainright, Christopher C. Curran   +7 more
doaj   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Embracing the mental health challenges of uterus transplant candidates

Acta Obstetricia et Gynecologica Scandinavica
Uterus transplantation (UTx) has emerged from clinical trials and is expected to become the standard of care for uterine factor infertility. Uterus transplant candidates historically have had to meet strict eligibility criteria to participate in clinical
Muhammad Umaid Rabbani, Brittney Randolph, Samantha Fry, Emily A. Boydston, Paige M. Porrett   +4 more
doaj   +1 more source

Non-Puerperal Uterine Inversion

Journal of the Belgian Society of Radiology, 2016
We report a case of non-puerperal uterine inversion, illustrating the correlation between MRI and pre-operation macroscopic images.
Isabelle Leconte, Cecile Thierry, Antony Bongiorno, Mathieu Luyckx, Latifa Fellah   +4 more
doaj   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Morphological assessment and characterization of uterine caruncles in Bengal goats

Ovozoa: Journal of Animal Reproduction
This study aimed to evaluate and characterize the gross, histologic and ultrasonographic features of uterine caruncles in Bengal goats, an indigenous breed in Bangladesh.  A total of 40 uteri were collected from sexually mature, pregnant and non-pregnant
Hafsa Hossain, Md. Rashedul Islam, Maksuda Taslima, Mozahidul Islam Tuser, Nurjahan Akter Juli, Al Wasef, Mahfuzul Islam, Jahagir Alam   +7 more
doaj   +1 more source

Regulation by Gonadal Steroids of Estrogen and Progesterone Receptors Along the Reproductive Tract in Female Lambs

Acta Veterinaria Scandinavica, 2001
The regulation of estrogen and progesterone receptor (ER, PR) expression by estradiol (E2) and progesterone (P4) in the oviduct, uterus and cervix of female lambs was studied. The animals received three intramuscular injections of E2, P4 or vehicle with
Rodríguez-Piñón M, Garófalo EG, Meikle A, Tasende C, Sahlin L   +4 more
doaj   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source