This study characterized 56 Escherichia coli isolates obtained from canine pyometra, which predominantly belonged to phylogroup B2 and harboured multiple virulence genes, with high multidrug resistance rates indicating potential clinical and zoonotic risks. ABSTRACT The presence of multidrug‐resistant extraintestinal pathogenic Escherichia coli (ExPEC)
İnci Başak Müştak +4 more
wiley +1 more source
The sublingual vaccine MV140 is dominant over prophylactic antibiotics for the prevention of recurrent, uncomplicated urinary tract infections in adult women A cost-utility analysis. [PDF]
Doiron RC, Nickel JC, Kamdar S.
europepmc +1 more source
ABSTRACT Talquetamab is a GPRC5D × CD3 bispecific antibody approved for relapsed/refractory multiple myeloma (RRMM). This is the first real‐world study to comprehensively report muco‐cutaneous toxicities, infections, and efficacy of talquetamab in 151 patients across five countries with the longest follow‐up reported enabling better efficacy and ...
Murali Janakiram +94 more
wiley +1 more source
Diabetes and hyperglucosuria exacerbate the severity of urinary tract infection caused by uropathogenic <i>E</i>. <i>coli</i> in the mouse model. [PDF]
Neupane S +7 more
europepmc +1 more source
A randomized phase 1b/2 trial of ABBV‐916 in adults with early Alzheimer's disease
Abstract INTRODUCTION ABBV‐916, an anti‐amyloid immunotherapy, was evaluated in patients with early Alzheimer's disease (AD). METHODS This phase 1b/2, double‐blind, placebo‐controlled study consisted of two stages: multiple ascending dose (Stage A) and dose expansion (Stage B).
Shau Yu Lynch +9 more
wiley +1 more source
Calprotectin as a Diagnostic Marker for Lower Respiratory Tract Infection and Sepsis in the Emergency Department. [PDF]
Wollmer M +4 more
europepmc +1 more source
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez +2 more
wiley +1 more source
Neither tranexamic acid nor ulinastatin affects the activated clotting time values in healthy volunteers and heparinized cardiovascular surgery patients. [PDF]
Jia B +3 more
europepmc +1 more source
Abstract Introduction Active surveillance of adverse events using healthcare data is emerging as complementary to the monitoring of spontaneous reports and stand‐alone pharmacoepidemiologic studies. The risk of urinary tract infections (UTIs) was listed as a special warning for sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) when marketed in Europe
Haoxin Le +5 more
wiley +1 more source
Diagnostic tests for urinary tract infections and antimicrobial resistance-a reality check between diagnostic innovation and implementation: a critical narrative review. [PDF]
Mohan V, Mitsakakis K.
europepmc +1 more source

