Results 161 to 170 of about 60,712 (301)

Uncertainty and utilitarian moral decision-making [PDF]

A long history of research in philosophy, psychology and neuroscience has explored moral utilitarian research questions, decision mechanisms and behaviour. For example, in the question ‘Is it appropriate for you to sacrifice one workman in order to save
Alzahrani, S.
core   +1 more source

Effects of promotional and preventive framing strategies in AI generated content on neural responses and trust. [PDF]

Sci Rep
Wang X, Alves RR, Hu Q, Chen H.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Utilitarian Preferences and Potential Games

, 2013
We study games with utilitarian preferences: the sum of individual utility functions is a generalized ordinal potential for the game. It turns out that generically, any finite game with a potential, ordinal potential, or generalized ordinal potential is ...
Salonen, Hannu
core  

Navigating Conflicts of Duty in Contexts of Compassionate Care: Utilitarian Reasoning as a Practice-Oriented Framework. [PDF]

Nurs Inq
Ayala R, Castillo D, Pariseau-Legault P.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Utilitarianism ،Utilitarian ،Utility (إنكليزيّة)

, 2023
openaire   +1 more source

Research on incentive mechanisms for veterans' participation in grassroots governance: An analysis based on behavioral expectations. [PDF]

PLoS One
Wang S, Zhang Z.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Perceived Benefits of Loyalty Programs: Scale Development and Implications for Relational Strategies [PDF]

Positive outcomes of loyalty programs are clear for firms, yet little research examines customer perceptions. To address this gap, this article investigates various perceived benefits of loyalty programs using a multi-benefit framework based on ...
Aîda Mimouni-Chaabane, Pierre Volle
core