Results 141 to 150 of about 3,744,885 (347)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Multi-access edge computing scheduling optimization model for remote education under 6G network environment based on reinforcement learning. [PDF]

Sci Rep
Jin L, Gao X, Wang J, Yuan S.
europepmc   +1 more source

Unroofed Coronary Sinus in a Dog: Diagnostic Utility of ECG-Gated Computed Tomography [PDF]

N. Ito, Risa Okamoto, Kazumi Shimada, Daigo Azakami, Zeki Yılmaz, Ryou Tanaka, Lina Hamabe   +6 more
openalex   +1 more source

Zenith: Utility-Aware Resource Allocation for Edge Computing

International Conference on Edge Computing [Services Society], 2017
Jinlai Xu, Balaji Palanisamy, Heiko Ludwig, Qingyang Wang   +3 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Joint energy-aware task offloading and privacy protection in healthcare monitoring systems via deep reinforcement learning. [PDF]

Sci Rep
Zhang J, Hu Y, Shao M, Li X.
europepmc   +1 more source

Reliability in the utility computing era: Towards reliable Fog computing

International Conference on Systems, Signals, and Image Processing, 2013
Henrik Madsen, G. Albeanu, B. Burtschy, F. Popențiu-Vlădicescu   +3 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Multi-agent reinforcement learning driven resource game optimization for network slicing in MEC-enabled HetNets. [PDF]

Sci Rep
Mao K.
europepmc   +1 more source

Safeguarding Surgeons: Utility of Ultrasonography and Computed Tomography in Reducing Diagnostic Errors in Acute Appendicitis

, 2019
MM Ramashankar, Rahul Pandey, Vipin Chandra Saini, S Kumar   +3 more
openalex   +1 more source