Results 41 to 50 of about 3,600,070 (348)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Cluster management of computing resources

MATEC Web of Conferences, 2016
The study suggests management of computing resources through set-theoretic clustering. The research proposes production modelling of knowledge — rules of managing explicit and fuzzy structures, according to their technical specifications: sustem ...
Ruchkin V.N., Makhmudov M.N., Romanchuk V.A., Fulin V.A., Kostrov B.V.   +4 more
doaj   +1 more source

Utility-Centric Service Provisioning in Multi-Access Edge Computing

Applied Sciences, 2019
Recently, multi-access edge computing (MEC) is a promising paradigm to offer resource-intensive and latency-sensitive services for IoT devices by pushing computing functionalities away from the core cloud to the edge of networks.
Xuan-Qui Pham, Tien-Dung Nguyen, VanDung Nguyen, Eui-Nam Huh   +3 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Users' experience matter: Delay sensitivity-aware computation offloading in mobile edge computing

Digital Communications and Networks, 2022
As a promising computing paradigm, Mobile Edge Computing (MEC) provides communication and computing capability at the edge of the network to address the concerns of massive computation requirements, constrained battery capacity and limited bandwidth of ...
Mingzhi Wang, Tao Wu, Tao Ma, Xiaochen Fan, Mingxing Ke   +4 more
doaj  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

A Budget Constraint Incentive Mechanism Based on Risk Preferences of Collaborators in Edge Computing

Mathematics
Mobile Edge Computing (MEC) is a new distributed computing method based on the mobile communication network. It can provide cloud services and an IT service environment for application developers and service providers at the edge of the network ...
Deng Li, Rongtao Hao, Zhenyan Wei, Jiaqi Liu   +3 more
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

MARL based resource allocation scheme leveraging vehicular cloudlet in automotive-industry 5.0

Journal of King Saud University: Computer and Information Sciences, 2023
Automotive-Industry 5.0 will use Beyond Fifth-Generation (B5G) communications to provide robust, abundant computation resources and energy-efficient data sharing among various Intelligent Transportation System (ITS) entities.
Manzoor Ahmed, Jinshi Liu, Muhammad Ayzed Mirza, Wali Ullah Khan, Fahd N. Al-Wesabi   +4 more
doaj  

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source