Results 51 to 60 of about 3,744,885 (347)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

PACU: Precision agriculture computational utilities

open access: yesSoftwareX
The field of precision agriculture relies on collecting and processing several types of data to assess temporal and spatial variability. We developed the pacu R package to provide a comprehensive and transparent framework for precision agriculture applications.
Caio L. dos Santos, Fernando E. Miguez
openaire   +2 more sources

A2HA—automatic and adaptive host allocation in utility computing for bag-of-tasks

open access: yesJournal of Internet Services and Applications, 2011
There are increasingly more computing problems requiring lengthy parallel computations. For those without access to current cluster or grid infrastructures, a recent and proven viable solution can be found with on-demand utility computing infrastructures,
João Nuno de Oliveira e Silva   +2 more
semanticscholar   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

O149 The utility of chest computed tomography in the staging of pancreatic cancer: a retrospective observational study [PDF]

open access: bronze, 2023
Raisa Jaffer   +6 more
openalex   +1 more source

A Budget Constraint Incentive Mechanism Based on Risk Preferences of Collaborators in Edge Computing

open access: yesMathematics
Mobile Edge Computing (MEC) is a new distributed computing method based on the mobile communication network. It can provide cloud services and an IT service environment for application developers and service providers at the edge of the network ...
Deng Li   +3 more
doaj   +1 more source

A DAQM-Based Load Balancing Scheme for High Performance Computing Platforms

open access: yesIEEE Access, 2017
This paper addresses the load balancing problem, which is one of the key issues in high-performance computing (HPC) platforms. A novel method, called decentralized active queue management (DAQM), is proposed to provide a fair task distribution in a ...
Kaijun Yang   +3 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Cluster management of computing resources

open access: yesMATEC Web of Conferences, 2016
The study suggests management of computing resources through set-theoretic clustering. The research proposes production modelling of knowledge — rules of managing explicit and fuzzy structures, according to their technical specifications: sustem ...
Ruchkin V.N.   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy