Results 71 to 80 of about 3,600,070 (348)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

AI-based big data analytics model for medical applications

open access: yesMeasurement: Sensors, 2022
Today, people's daily lives depended on their mobile phones, facilitating many beneficial tasks. Mobile computing and cloud computing combine cloud-based mobile computing to improve their features and overcoming their disadvantages such as memory space ...
S. Lokesh   +5 more
doaj  

Greening emerging IT technologies: techniques and practices

open access: yesJournal of Internet Services and Applications, 2017
The tremendous increase in global industrial activity has resulted in high utilization of natural energy resources and increase in global warming over the last few decades. Meanwhile, computing has become a popular utility of modern human lifestyle. With
Junaid Shuja   +7 more
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Resource management in blockchain-enabled heterogeneous edge computing system

open access: yesTongxin xuebao, 2020
In blockchain-enabled mobile edge computing (BMEC) systems,a new class of blockchain application related computation tasks was introduced to the system.Due to the differences of parallelism among computation tasks,heterogenous computing framework was ...
Ping ZHANG   +4 more
doaj   +2 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Memory-optimized distributed utility mining for big data

open access: yesJournal of King Saud University: Computer and Information Sciences, 2022
In recent days, social media, online services, smartphones, and the Internet of Things (IoT) produces large quantities of data every second. The generated data is structured, unstructured, or semi-structured and available in various formats.
Sunil kumar, Krishna Kumar Mohbey
doaj  

The Utility of Computed Tomography in Colonie Diverticulitis

open access: yesAnnals of Surgery, 1986
Forty-one patients admitted to our hospital during an 18-month period with the clinical diagnosis of colonic diverticulitis were analyzed to evaluate the utility of computed tomography (CT). Abdominal pain and leukocytosis were the most common presenting manifestations, 75 and 66%, respectively.
Thomas A. Stellato   +3 more
openaire   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

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