Results 81 to 90 of about 3,744,885 (347)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Utility of Cone-Beam Computed Tomography in the Detection of Low Bone Mass—A Systematic Review [PDF]
, 2023 Ioana Ruxandra Poiană +4 more
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
2HD: Hybrid Dynamic Utility-Driven Dependency-Aware Task Scheduling in Heterogeneous Datacenters
IEEE AccessMost dependency-aware task scheduling algorithms are formulated with an optimization objective of minimizing makespan. In this paper, we directed our research towards algorithms which optimize for early availability of partial output data in ...
Roxana-Gabriela Stan, Florin Pop
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Greening emerging IT technologies: techniques and practices
Journal of Internet Services and Applications, 2017 The tremendous increase in global industrial activity has resulted in high utilization of natural energy resources and increase in global warming over the last few decades. Meanwhile, computing has become a popular utility of modern human lifestyle. With
Junaid Shuja +7 more
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Resource management in blockchain-enabled heterogeneous edge computing system
Tongxin xuebao, 2020 In blockchain-enabled mobile edge computing (BMEC) systems,a new class of blockchain application related computation tasks was introduced to the system.Due to the differences of parallelism among computation tasks,heterogenous computing framework was ...
Ping ZHANG +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source