Results 61 to 70 of about 617,005 (216)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An Integrated Bandwidth Adaptation Scheme for Multimedia Wireless Networks and its Connection-Level Performance Analysis

open access: yesJournal of Communications Software and Systems, 2006
This paper presents an integrated bandwidth adaptation scheme for multimedia wireless networks using application utility functions. With the proposed scheme, each call in the network is assigned a utility function according to itsadaptive characteristics.
Ning Lu, John Bigham
doaj  

Identifyingy the Utility Function of Transport Services From Stated Preferences

open access: yesTransport and Telecommunication, 2015
The aim of this study was to analyze the modal shift of passengers by analyzing their preferences. If the preferences of passengers are known it is possible to build up mathematically their utility function.
Andrejszki Tamas   +2 more
doaj   +1 more source

Optimal outcome sharing with a consortium of contractors

open access: yesJournal of Civil Engineering and Management, 2016
Where a consortium of contractors is involved, there exist no guidelines in the literature on what the outcome sharing arrangement should be. The paper addresses this shortfall. It derives the optimal outcome sharing arrangement for risk-neutral and risk-
S. Mahdi Hosseinian, David G. Carmichael
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Dynamics of Population Patch Distribution

open access: yesМоделирование и анализ информационных систем, 2018
The problem of selection by the patch population in the absence of information on the utility of the patch, that is, the volume of its energy resources, is considered. This problem relates to the theory of optimal foraging. U.
Alexander N. Kirillov, Inna V. Danilova
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

SOME PROPERTIES OF THE VARIATIONAL PROBLEMS OF OPTIMAL CONTROL OF CONSUMPTION

open access: yesСтатистика и экономика, 2016
ARTICLE RETRACTEDIn this paper we study the General patterns of models based on variational methods in various problems of optimal control of consumption: decisionmaking in the management of the household, as well as models of the economic dynamics of ...
Alla Yu. Meyerson   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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