Results 241 to 250 of about 3,539,215 (285)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Carbohydrate Storage and Supplementation Strategies for Peak Performance in Cross-Country Skiing. [PDF]

Scand J Med Sci Sports
Ørtenblad N, Holmberg HC, Nybo L, Gejl KD.   +3 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Donor Time to Death and DCD Liver Transplant Outcomes: Challenging the Dogma That Shorter Is Better. [PDF]

Transplant Direct
Amarnath DR, Tingle SJ, Kourounis G, Malik AK, Roll GR, Freise C, Yamaguchi S, Rickert C, Wilson CH.   +8 more
europepmc   +1 more source

Health care utilization and costs associated with acute exacerbation of fibrosing interstitial lung disease in the United States: A retrospective administrative claims database analysis. [PDF]

J Manag Care Spec Pharm
Yang J, Sadowski K, Mercer D, Zeldow B, Manjarres DG.   +4 more
europepmc   +1 more source

Emergency Department Utilization and Outpatient Care Continuity Among White and Hispanic Patients With Inflammatory Bowel Disease at a County Health System. [PDF]

Cureus
Orosa M, Chang A.
europepmc   +1 more source

Impact of a complex intervention in primary care for patients with palliative care needs in their healthcare utilization: a before-after study. [PDF]

Prim Health Care Res Dev
Seiça Cardoso C, Prazeres F, Nunes C, Simões P, Aires C, Rita P, Penetra J, Lopes P, Alcobia S, Gomes B.   +9 more
europepmc   +1 more source

Social determinants of oral health among adults in Saudi Arabia: a narrative review. [PDF]

Saudi Dent J
Alsaif MI.
europepmc   +1 more source

Incidence, Risk Factors, and Reasons for Emergency Department Utilization 90 Days After Achilles Tendon Repair. [PDF]

Orthop J Sports Med
Holle AM, Lin E, Driggs A, Tummala SV, Patel K.   +4 more
europepmc   +1 more source

Problems of resource utilization [PDF]

anonymous
core