Results 241 to 250 of about 1,546,803 (298)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Greater reactivity to stressors as an indicator of service utilization and need in veteran women with sexual assault histories. [PDF]

Psychol Serv
Metts A, Pearson R, Roe K, McGuire AP, Zlotnick C, Creech SK.   +5 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Patterns of drug prescription among hospitalized patients in a tertiary women's hospital: A retrospective drug utilization study. [PDF]

J Int Med Res
Omidifar N, Mahi-Birjand M, Askari P, Abolzadeh Oskuie P, Karimzadeh I, Mirjalili M, Hoorang M, Peymani P.   +7 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

How can the Multiple Errands Test be utilized in occupational therapy to evaluate daily living skills in stroke patients?

Tripdatabase
openalex   +1 more source

Manpower Requirement and Utilization in Secondary Schools in Delta North: Challenges and the Way Forward

Oduma, Justice O., OSEGI, Michael
openalex   +1 more source

Enhancing frequency support utilizing smart transformers in RES-dominated power systems integrated with fractional order controller

Chakka Bapi Ayyappa Raju, Sanjoy Debbarma, Rayapudi Srinivasa Rao, Liza Debbarma   +3 more
openalex   +1 more source

Table 1_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-series analysis.docx

Matteo Puntoni (4901191), Caterina Caminiti (3412628), Giuseppe Maglietta (12992976), Marcello Lanari (3533234), Giacomo Biasucci (5412437), Agnese Suppiej (11782133), Federico Marchetti (167802), Alessandro De Fanti (16361411), Fabio Caramelli (8117402), Lorenzo Iughetti (830764), Chiara Ghizzi (15228626), Enrico Valletta (65730), Gianluca Vergine (18403392), Marcello Stella (8482674), Beatrice Campana (22099826), Valentina Fainardi (12222593), Michela Deolmi (21027068), Susanna Esposito (397772), Emilia-Romagna Paediatric COVID-19 Network (22099829)   +18 more
openalex   +1 more source