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Efficacy of baloxavir marboxil against bovine H5N1 virus in mice [PDF]

open access: yesNature Communications
Since the first detection of highly pathogenic avian influenza (HPAI) H5N1 (clade 2.3.4.4b) in U.S. dairy cattle in early 2024, the virus has spread rapidly, posing a major public health concern as the number of human cases continues to rise.
Maki Kiso   +3 more
doaj   +2 more sources

Patient and Clinician Experiences When Using a CO2 Laser for Cavity Preparations: Lessons learned from Prospective Clinical Research

open access: yesApplied Sciences, 2022
This prospective clinical study evaluated the experiences and preferences of both patients and clinicians when performing class I–V cavity preparation procedures using a 9300 nm CO2 laser without anesthetic.
Gregory Schuster   +4 more
doaj   +1 more source

Ellagic Acid and Schisandrins: Natural Biaryl Polyphenols with Therapeutic Potential to Overcome Multidrug Resistance in Cancer

open access: yesCells, 2021
Multidrug resistance (MDR) is one of the major clinical challenges in cancer treatment and compromises the effectiveness of conventional anticancer chemotherapeutics.
Sabesan Yoganathan   +3 more
doaj   +1 more source

A Peer Educational Tool to Promote Antimicrobial Stewardship on a University Campus

open access: yesPharmacy, 2021
Antibiotic resistance is a major public health threat. Patient education on the appropriate use of antibiotics is a key component in combating antimicrobial resistance.
Yuman (Yumi) Lee, Nicole Bradley
doaj   +1 more source

The Arts and Utopia [PDF]

open access: yesIn Medias Res, 2023
The position on utopia is the position on reality. Utopia is the theme of many works of art, one can even claim that the arts are the ultimate description of utopia, and the arts strive to achieve utopia.
Predrag Finci
doaj   +1 more source

COVID-19: Characteristics and Therapeutics

open access: yesCells, 2021
Novel coronavirus (COVID-19 or 2019-nCoV or SARS-CoV-2), which suddenly emerged in December 2019 is still haunting the entire human race and has affected not only the healthcare system but also the global socioeconomic balances.
Rameswari Chilamakuri, Saurabh Agarwal
doaj   +1 more source

Antifungal Activity of Novel Formulations Based on Terpenoid Prodrugs against C. albicans in a Mouse Model

open access: yesPharmaceutics, 2021
Carvacrol (CAR), a phenolic monoterpenoid, has been extensively investigated for its antimicrobial and antifungal activity. As a result of its poor physicochemical properties, water soluble carvacrol prodrugs (WSCPs) with improved water solubility were ...
Suvidha Menon   +7 more
doaj   +1 more source

Splicing Regulation of Pro-Inflammatory Cytokines and Chemokines: At the Interface of the Neuroendocrine and Immune Systems

open access: yesBiomolecules, 2015
Alternative splicing plays a key role in posttranscriptional regulation of gene expression, allowing a single gene to encode multiple protein isoforms.
Felitsiya Shakola   +2 more
doaj   +1 more source

E-topia: Utopia after the Mediated Body [PDF]

open access: yes, 2017
open access journalA custom-made media installation, diplorasis, will be used to explore the body in digital media. This mediated body attempts to re-think how the Deleuzian time-image is translated from its cinematic confinement to the space of new ...
Themistokleous, George
core   +2 more sources

Transcriptional Regulation of Chemokine Expression in Ovarian Cancer

open access: yesBiomolecules, 2015
The increased expression of pro-inflammatory and pro-angiogenic chemokines contributes to ovarian cancer progression through the induction of tumor cell proliferation, survival, angiogenesis, and metastasis.
Bipradeb Singha   +2 more
doaj   +1 more source

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