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UTP-Hexose-1-phosphate uridylyltransferase

open access: closed, 2007
Ida Schomburg   +2 more
openaire   +2 more sources
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Remodeling hexose-1-phosphate uridylyltransferase: mechanism-inspired mutation into a new enzyme, UDP-hexose synthase.

Biochemistry, 1990
Hexose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-galactose and glucose-1-P with UDP-glucose and galactose-1-P by a double-displacement mechanism through a covalent intermediate (E-UMP), in which UMP is bonded to one of two ...
Jeongmin Kim, F. Ruzicka, Perry A. Frey
semanticscholar   +1 more source

Kinetic mechanism of UDP-hexose synthase, a point variant of hexose-1-phosphate uridylyltransferase from Escherichia coli.

Biochemistry, 1998
Galactose-1-phosphate (galactose-1-P) uridylyltransferase from Escherichia coli catalyzes the interconversion of UDP-glucose and galactose-1-P with UDP-galactose and glucose-1-P by a double-displacement mechanism through a uridylyl-enzyme intermediate ...
F. Ruzicka, S. Geeganage, P. Frey
semanticscholar   +1 more source

Identification and characterization of a strict and a promiscuous N-acetylglucosamine-1-P uridylyltransferase in Arabidopsis.

Biochemical Journal, 2010
UDP-GlcNAc is an essential precursor for glycoprotein and glycolipid synthesis. In the present study, a functional nucleotidyltransferase gene from Arabidopsis encoding a 58.3 kDa GlcNAc1pUT-1 (N-acetylglucosamine-1-phosphate uridylyltransferase) was ...
Ting Yang   +3 more
semanticscholar   +1 more source

Restoring galactose metabolism without restoring GALT rescues both compromised survival in larvae and an adult climbing deficit in a GALT‐null D. Melanogaster model of classic galactosemia

Journal of Inherited Metabolic Disease
Classic galactosemia (CG) is an autosomal recessive disorder that results from profound deficiency of galactose‐1‐phosphate uridylyltransferase (GALT), the middle enzyme in the highly conserved Leloir pathway of galactose metabolism.
Jennifer M. I. Daenzer   +2 more
semanticscholar   +1 more source

Transcriptome scale analysis to decode the differential sucrose accumulation mechanisms in sugarcane under the effect of gibberellin.

Physiologia Plantarum : An International Journal for Plant Biology
In the present study, we analyzed GA3 (gibberellin)-treated sugarcane samples at the transcriptomic level to elucidate the differential expression of genes that influence sucrose accumulation.
Kriti Roopendra   +4 more
semanticscholar   +1 more source

Novel proteomic biomarker panel for prediction of aggressive metastatic hepatocellular carcinoma relapse in surgically resectable patients.

Journal of Proteome Research, 2014
The natural course of early HCC is unknown, and its progression to intermediate and advanced HCC can be diverse. Some early stage HCC patients enjoy prolonged disease-free survival, whereas others suffer aggressive relapse to stage IV metastatic cancer ...
G. S. Tan   +6 more
semanticscholar   +1 more source

The UTP-glucose-1-phosphate uridylyltransferase of Brucella melitensis inhibits the activation of NF-κB via regulating the bacterial type IV secretion system.

International Journal of Biological Macromolecules, 2020
Yucheng Zhou   +9 more
semanticscholar   +1 more source

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