Utrophin - Open Access .click

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REVIEW: The membrane--cytoskeleton interface: the role of dystrophin and utrophin

Journal of Muscle Research & Cell Motility, 1997
Recent studies with transgenic animals have considerably advanced our knowledge of the roles of dystrophin and utrophin in both muscle and non-muscle tissues. Rigorous analyses of the roles of the various mdx mutations in mice, as well as the use of artificial transgenes in an mdx background, are beginning to define the functional importance of various
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Utrophin to the rescue

Nature, 1996
Rachelle H. Crosbie, Kevin P. Campbell
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Structural comparison of actin binding in utrophin and dystrophin

Neurological Sciences, 2000
Dystrophin links the actin cytoskeleton to the dystroglycan complex in the plasma membrane as part of the linkage between the cytoskeleton and the extracellular matrix. Damage to or absence of dystrophin causes Duchenne or Becker muscular dystrophy. It has been proposed that elevating the levels of utrophin, a close homologue of dystrophin, may act as ...
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Utrophin euphoria

Neuromuscular Disorders, 1997
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Calmodulin regulation of utrophin actin binding