Results 51 to 60 of about 34,232 (289)

Development and Validation of UV-Spectrophotometric Method for Estimation of Vinpocetine in Marketed Formulation and Nanoformulation

, 2023
A quick, accurate, and cost-effective UV spectroscopy method was developed to estimate the Vinpocetine concentration in bulk, tablet dosage formulations and niosomes formulations, using a solvent ratio of (6:4) methanol: water.
Chimagave, Supriya, Patil, Swapnil, Kurangi, Bhaskar, Soudagar, Moazzim, Kumar HB, Chethan   +4 more
core   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Rediscovering Sodium Ionophores as Selective Agents for Lithium Recognition and Extraction

Angewandte Chemie, EarlyView.
Long‐classified sodium ionophores unexpectedly prefer lithium and act as efficient extractants in solid–liquid extraction (SLE). Readily prepared from catechol and haloacetamides, these hosts recover hydrated LiCl from multicomponent salt mixtures via a hydration‐assisted O···Li+ binding mode, enabling scalable lithium separation with Li/Na, Li/K, and ...
Jakub Narodowiec, Aleksandra Kazimierczak, Małgorzata Grela, Magdalena Ceborska, Magdalena Matczuk, Maja Morawiak, Kajetan Dąbrowa   +6 more
wiley   +2 more sources

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration

Angewandte Chemie, EarlyView.
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti, Hannah Dreisbach, Rémi Corlay, Clara Weber, Tamara Reiter, Wael Elaily, Bastian Daniel, Klaus Zangger, Pedro A. Sánchez‐Murcia, Mélanie Hall   +9 more
wiley   +2 more sources

DETERMINATION OF LACIDIPINE IN PRESENCE OF ITS ACID-INDUCED DEGRADATION PRODUCT IN BULK AND PHARMACEUTICAL DOSAGE FORM BY FIRST DERIVATIVE, DUAL WAVELENGTH AND SIMULTANEOUS EQUATION UV SPECTROPHOTOMETRIC METHODS [PDF]

Al-Azhar Journal of Pharmaceutical Sciences
Three simple, precise and economical  UV spectrophotometric methods  have been developed for the estimation of lacidipine and its degradation product  in bulk  and pharmaceutical formulations.
Abdalla El-Shanawany, Khalid Attia, Mohamed Hasan   +2 more
doaj   +1 more source

Validated UV-Visible Spectrophotometric Method for Quantitative Analysis of Glycyrrhizin

Aim: The study aimed to develop and validate a simple, accurate, precise and cost-effective UV-Visible spectrophotometric method for the estimation of Glycyrrhizin in bulk as well as in formulation.
Wakte, Pravin, Bhusari, Sachin, More , Bhagyashri   +2 more
core   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Predicting antioxidant activity of wood vinegar using color and spectrophotometric parameters

MethodsX, 2020
Wood vinegar can be produced from many types of raw materials using different pyrolysis methods resulting in potentially different antioxidant activity.
Krittaya Petchpoung, Siriwan Soiklom, Wipada Siri-anusornsak, Nathawat Khlangsap, Anucha Tara, Thanapoom Maneeboon   +5 more
doaj   +1 more source

Utilization of green analytical chemistry principles for the simultaneous estimation of paracetamol, aceclofenac and thiocolchicoside by UV spectrophotometry

Green Chemistry Letters and Reviews, 2021
The present paper describes multicomponent UV spectrophotometric method for the determination of paracetamol, aceclofenac, and thiocolchicoside based on the fundamentals of green analytical chemistry.
K. S. Kokilambigai, K. S. Lakshmi
doaj   +1 more source