Results 41 to 50 of about 40,730 (262)
Advanced Science, EarlyView.Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang +9 more
wiley +1 more source
The Role of Complement System’s C3 and C4 Fractions in the Pathogenesis of Herpetic Uveitis
Клинический разбор в общей медицинеHerpetic anterior uveitis is mainly considered as acute unilateral anterior uveitis with non-granulomatous, granulomatous, or stellate keratic precipitates, which is associated with iris atrophy, decreased corneal sensation, and an acute rise in the ...
Lusine V. Kambulyan +3 more
doaj +1 more source
Arthritis Research & Therapy, 2018 Background Anterior uveitis is the most common extra-articular manifestation of ankylosing spondylitis (AS). AS-related anterior uveitis frequently presents as acute, recurrent iridocyclitis; therefore, AS is often initially suspected by an ...
Baek-Lok Oh +4 more
doaj +1 more source
Rhegmatogenous retinal detachment masquerading as exudative panuveitis with intense anterior chamber inflammatory reaction. [PDF]
, 2020 Purpose:This is a retrospective case report illustrating the diagnostic and therapeutic challenges associated with a chronic rhegmatogenous retinal detachment masquerading as a severe panuveitis with intense anterior chamber inflammation.
Bhisitkul, Robert B +3 more
core
Magnetically Controllable and Degradable Milliscale Swimmers as Intraocular Drug Implants
Advanced Science, EarlyView.Magnetically controllable degradable milliscale swimmers (MDMS) offer a promising alternative to commercial intraocular drug implants, reducing complications like implant dislocation and uncontrolled drug release. MDMS achieve high velocities in ocular environments, enable real‐time imaging, and deliver drugs effectively without disrupting retinal ...
Erdost Yildiz +8 more
wiley +1 more source
Journal of Ophthalmology, 2015 Background: Given the complex pathogenetic mechanism of the development of uveitis, it is important to investigate the features of the interaction between the immune, vascular and nervous systems, the level of their activity, and the potential for ...
N.I. Khramenko
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective This study aims to assess the risk of noninfectious uveitis (NIU) relapse in pediatric patients undergoing adalimumab (ADA) tapering, evaluating potential predictors of such risk. Methods We conducted a multicenter retrospective cohort study involving pediatric patients with NIU who underwent ADA tapering due to inactive uveitis.
Achille Marino +31 more
wiley +1 more source
Atezolizumab-induced bilateral anterior uveitis: A case report
American Journal of Ophthalmology Case Reports, 2021 Purpose: To report a case of bilateral anterior uveitis undergoing atezolizumab treatment for advanced non-small cell lung cancer (NSCLC). Observations: A 64-year-old man was receiving atezolizumab for metastatic programmed cell death ligand 1 (PD-L1 ...
Tsuyoshi Mito +3 more
doaj
Choroidal change in acute anterior uveitis associated with human leukocyte antigen-B27. [PDF]
PLoS ONE, 2017 To evaluate choroidal changes in eyes with acute anterior uveitis associated with human leukocyte antigen (HLA)-B27.In 44 patients with first-onset, unilateral, acute-onset (
Seong Joon Ahn +2 more
doaj +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 2021 Cytomegalovirus (CMV) is a member of the Herpesviridae family, including viruses that are well-known agents of keratitis, anterior uveitis, scleritis and retinitis.
Caroline dos Reis +5 more
doaj +1 more source